The axon initial segment (AIS), located within the first 30 μm of the axon, has two essential
roles in generating action potentials and maintaining axonal identity. AIS assembly depends …

The axon initial segment (AIS) is a highly specialized neuronal compartment that plays a key
role in neuronal development and excitability. It concentrates multiple membrane proteins …

The axon initial segment ( AIS ) plays a central role in electrogenesis and in the maintenance
of neuronal polarity. Its molecular organization is dependent on the scaffolding protein …

The tetrodotoxin‐resistant ( TTX ‐R) voltage‐gated sodium channel Na v 1.8 is predominantly
expressed in peripheral afferent neurons, but in case of neuronal injury an ectopic and …

The architecture of the actin cytoskeleton that concentrates at presynapses remains poorly
known, hindering our understanding of its roles in synaptic physiology. In this work, we …

Combining and multiplexing microscopy approaches is crucial to understand cellular events,
but requires elaborate workflows. Here, we present a robust, open-source approach for …

Single-molecule localization microscopy (SMLM) can reach sub-50 nm resolution using
techniques such as stochastic optical reconstruction microscopy (STORM) or DNA-point …

Synapses are the nexus of signal transmission in the nervous system. Despite decades of
work, the architecture of the actin cytoskeleton that concentrates at presynapses remain poorly …

Neuronal clathrin-mediated endocytosis has unique features in compartments such as
dendrites and presynaptic boutons, but how membrane and extracellular components are …

… We thank Stephanie Angles-d’Ortoli and Fanny Rueda-Boroni for expert technical assistance.
This work was supported by Marie Curie 7th framework program Grant IRG-2008-239499 (…