While histological changes in microglia have long been recognized as a pathological
feature of Alzheimer's disease (AD), recent genetic association studies have also strongly …

Minocycline, a second generation broad‐spectrum antibiotic, has been frequently postulated
to be a “microglia inhibitor.” A considerable number of publications have used minocycline …

The hemizygous R47H variant of triggering receptor expressed on myeloid cells 2 (TREM2),
a microglia-specific gene in the brain, increases risk for late-onset Alzheimer’s disease (AD)…

Alzheimer’s disease (AD), the most common form of dementia, is characterized by the abnormal
accumulation of amyloid plaques and hyperphosphorylated tau aggregates, as well as …

Sex is a key modifier of neurological disease outcomes. Microglia are implicated in
neurological diseases and modulated by microRNAs, but it is unknown whether microglial …

The R47H variant of triggering receptor expressed on myeloid cells 2 (TREM2) increases
the risk of Alzheimer's disease (AD). To investigate potential mechanisms, we analyzed …

Patients with frontotemporal dementia (FTD) resulting from granulin (GRN) haploinsufficiency
have reduced levels of progranulin and exhibit dysregulation in inflammatory and …

TREM2 and Amyloid Beta: A Love-Hate Relationship Page 1 Neuron Previews TREM2 and
Amyloid Beta: A Love-Hate Relationship Joe Udeochu,1,2 Faten A. Sayed,1,3 and Li Gan1,2,3 …

Background The transmission of extended-spectrum beta-lactamase-producing enterobacteriaceae
(ESBL) is prevented by additional contact precautions, mainly relying on isolation in …

Background The prevalence of extended-spectrum beta-lactamase (ESBL)-producing
Enterobacteriaceae is increasing globally and is a major clinical concern. Between June 2008 …