I-PpoI is a homing endonuclease that has a high cleavage activity and specificity for a
conserved sequence within the ribosomal rDNA repeats, located in a single cluster on the …

It has been theorized that inducing extreme reproductive sex ratios could be a method to
suppress or eliminate pest populations. Limited knowledge about the genetic makeup and …

Genetic control aims to reduce the ability of insect pest populations to cause harm via the
release of modified insects. One strategy is to bias the reproductive sex ratio towards males so …

Malaria is a serious global health burden, affecting more than 200 million people each year
in over 90 countries, predominantly in Africa, Asia and the Americas. Since the year 2000, a …

Y chromosome function, structure and evolution is poorly understood in many species,
including the Anopheles genus of mosquitoes—an emerging model system for studying …

Despite its function in sex determination and its role in driving genome evolution, the Y
chromosome remains poorly understood in most species. Y chromosomes are gene-poor, repeat-…

In vertebrates, enzymes responsible for DNA methylation, one of the epigenetic mechanisms,
are encoded by genes falling into the cytosine methyltransferases genes family (Dnmt1, …

Although of high priority for the development of genetic tools to control malaria-transmitting
mosquitoes, only a few germline-specific regulatory regions have been characterised to date …

In the last two decades, surgical approach for hysterectomy has evolved significantly [1]. On
the one hand single-site surgery, minilaparoscopy and the more recent percutaneous …

Introduction The role of a molecular pattern predictive of hyperthermic intraperitoneal
chemotherapy (HIPEC) efficacy in advanced ovarian cancer (AOC) patients has been poorly …