In insects, rapidly evolving primary sex-determining signals are transduced by a conserved
regulatory module controlling sexual differentiation. In the agricultural pest Ceratitis capitata (…

Objectives The Global Aging & Geriatric Experiments in Bipolar Disorder Database (GAGE‐BD)
project pools archival datasets on older age bipolar disorder (OABD). An initial Wave 1 (…

Objectives The distinction between bipolar I disorder (BD‐I) and bipolar II disorder (BD‐II)
has been a topic of long‐lasting debate. This study examined differences between BD‐I and …

Background Cognitive deficits in bipolar disorder (BD) impact functioning and are main
contributors to disability in older age BD (OABD). We investigated the difference between OABD …

Mucosal surfaces such as fish gills interface between the organism and the external environment
and as such are major sites of foreign Ag encounter. In the gills, the balance between …

Objective Amongst psychiatric disorders, major depressive disorder (MDD) is the most
prevalent, by affecting approximately 15–17% of the population and showing a high suicide risk …

Background: Delirium is a common geriatric syndrome. Few studies have been conducted
in nursing home (NH) residents. The aim of this project was to perform a point prevalence …

Neuroinflammation represents a central feature in the development of Alzheimer’s disease (AD).
The resident innate immune cells of the brain are the principal players in …

Neurodegenerative diseases are chronic, progressive disorders that occur in the central
nervous system (CNS). They are characterized by the loss of neuronal structure and function …

The aim of this review is to critically analyze promises and limitations of pharmacological
inducers of autophagy against protein misfolding-associated neurodegeneration. Effective …