Searches for the genetic underpinnings of uniquely human traits have focused on human-specific
divergence in conserved genomic regions, which reflects adaptive modifications of …

Microsatellite expansions of CCTG repeats in the cellular nucleic acid-binding protein (CNBP)
gene leads to accumulation of toxic RNA and have been associated with myotonic …

Humans diverge from other primates in numerous ways, including their neuroanatomy and
cognitive capacities. Human-specific features are particularly prominent in the cerebral cortex…

During evolution, humans acquired extensive genomic changes that collectively define unique
features of our species, yet functions for these sequence variants are largely unknown. In …

Humans evolved an extraordinarily expanded and complex cerebral cortex, associated with
developmental and gene regulatory modifications. Human accelerated regions (HARs) are …

The exon junction complex (EJC), nucleated by EIF4A3, is indispensable for mRNA fate and
function throughout eukaryotes. Unexpectedly, we discover that EIF4A3 directly controls …

La Tesi si propone di analizzare la responsabilità della struttura sanitaria e dei dei medici
dipendenti sia sotto il profilo amministrativo che civile. Partendo dalla sua evoluzione storica, …

Rates of disease progression differ among patients with Alzheimer’s disease, but little is
known about prognostic predictors. The aim of the study was to assess whether …

Background/Aims: Visual deficits are frequent in Alzheimer’s disease (AD), yet little is known
about the nature of these disturbances. The aim of the present study was to investigate …

Background: Alzheimer disease (AD) has heterogeneous clinical manifestations. Different
neuropsychological profiles in AD patients might be indicative of the diffusion of the …