User profiles for Federico Roncaroli

Federico Roncaroli

Professor Clinical Neuropathology, University of Manchester
Verified email at manchester.ac.uk
Cited by 11135

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

…, SM Gentleman, B Serafini, F Aloisi, F Roncaroli… - Brain, 2011 - academic.oup.com
Meningeal inflammation in the form of ectopic lymphoid-like structures has been suggested
to play a prominent role in the development of cerebral cortical grey matter pathology in …

A gradient of neuronal loss and meningeal inflammation in multiple sclerosis

…, OW Howell, C Reeves, F Roncaroli… - Annals of …, 2010 - Wiley Online Library
Objective Prominent inflammation with formation of ectopic B‐cell follicle‐like structures in
the meninges in secondary progressive multiple sclerosis (MS) (SPMS) is associated with …

Reference and target region modeling of [11C]-(R)-PK11195 brain studies

…, P Edison, N Pavese, F Roncaroli… - Journal of Nuclear …, 2007 - Soc Nuclear Med
PET with [ 11 C]-(R)-PK11195 is currently the modality of choice for the in vivo imaging of
microglial activation in the human brain. In this work we devised a supervised clustering …

Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis

…, D Gveric, PA Muraro, R Nicholas, F Roncaroli… - Brain, 2012 - academic.oup.com
The primary progressive form of multiple sclerosis is characterized by accrual of neurological
dysfunction from disease onset without remission and it is still a matter of debate whether …

[HTML][HTML] Incidence and spectrum of sporadic Creutzfeldt–Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification

…, JPM Langeveld, A Ladogana, I Zerr, F Roncaroli… - Acta …, 2009 - Springer
Six subtypes of sporadic Creutzfeldt–Jakob disease with distinctive clinico-pathological
features have been identified largely based on two types of the abnormal prion protein, PrP Sc , …

The neuropathological basis of clinical progression in multiple sclerosis

R Reynolds, F Roncaroli, R Nicholas, B Radotra… - Acta …, 2011 - Springer
Multiple sclerosis is the major inflammatory condition affecting the central nervous system (CNS)
and is characterised by disseminated focal immune-mediated demyelination. …

Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia

…, M Paterno, H Christian, F Roncaroli… - The Journal of …, 2010 - journals.aai.org
The brain microenvironment is continuously monitored by microglia with the detection of
apoptotic cells or pathogens being rapidly followed by their phagocytosis to prevent …

New features in the redox coordination chemistry of metal nitrosyls {M–NO+; M–NO; M–NO−(HNO)}

F Roncaroli, M Videla, LD Slep, JA Olabe - Coordination Chemistry …, 2007 - Elsevier
We describe new developments in the coordination chemistry of bound nitrosyl, considering
its three formal redox states: NO + , NO and NO − /HNO. We emphasize on the correlation …

Landscape of Familial Isolated and Young-Onset Pituitary Adenomas: Prospective Diagnosis in AIP Mutation Carriers

…, S Ellard, AB Grossman, F Roncaroli… - The Journal of …, 2015 - academic.oup.com
Context: Familial isolated pituitary adenoma (FIPA) due to aryl hydrocarbon receptor
interacting protein (AIP) gene mutations is an autosomal dominant disease with incomplete …

Clinical and pathological aspects of silent pituitary adenomas

J Drummond, F Roncaroli, AB Grossman… - The Journal of …, 2019 - academic.oup.com
Context Silent pituitary adenomas are anterior pituitary tumors with hormone synthesis but
without signs or symptoms of hormone hypersecretion. They have been increasingly …