The synthetic neomycin‐sensing riboswitch interacts with its cognate ligand neomycin as
well as with the related antibiotics ribostamycin and paromomycin. Binding of these …

N 6 -Methyladenosine (m 6 A) is an abundant epitranscriptomic modification that plays important
roles in many aspects of RNA metabolism. While m 6 A is thought to mainly function by …

In this work an improved stable isotope labeling protocol for nucleic acids is introduced. The
novel building blocks eliminate/minimize homonuclear 13 C and 1 H scalar couplings thus …

N 6 -methyladenosine (m 6 A) is a post-transcriptional modification that controls gene expression
by recruiting proteins to RNA sites. The modification also slows biochemical processes …

RNA modifications are crucial factors for efficient protein synthesis. All classes of RNAs that
are involved in translation are modified to different extents. Recently, mRNA modifications …

We present the access to [5‐ 19 F, 5‐ 13 C]‐uridine and ‐cytidine phosphoramidites for the
production of site‐specifically modified RNAs up to 65 nucleotides (nts). The amidites were …

Measuring the strength of the hydrogen bonds between DNA base pairs is of vital importance
for understanding how our genetic code is physically accessed and recognized in cells, …

Using chemical synthesis and solution NMR spectroscopy, RNA structural ensembles
including a major ground state and minor populated excited states can be studied at atomic …

The rheology of mixed carrageenan gels was investigated at 15 mM calcium, 50 mM potassium
and 20 mM sodium concentration. Used carrageenans were of ι-, κ- and Furcellaran-type …

Although group II intron ribozymes are intensively studied the question how structural dynamics
affects splicing catalysis has remained elusive. We report for the first time that the group …