Towards targeting of shared mechanisms of cancer metastasis and therapy resistance
F Weiss, D Lauffenburger, P Friedl - Nature Reviews Cancer, 2022 - nature.com
Resistance to therapeutic treatment and metastatic progression jointly determine a fatal
outcome of cancer. Cancer metastasis and therapeutic resistance are traditionally studied as …
outcome of cancer. Cancer metastasis and therapeutic resistance are traditionally studied as …
[HTML][HTML] Immune response in COVID-19: what is next?
The coronavirus disease 2019 (COVID-19) has been a global pandemic for more than 2
years and it still impacts our daily lifestyle and quality in unprecedented ways. A better …
years and it still impacts our daily lifestyle and quality in unprecedented ways. A better …
Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation
Cohesin is important for 3D genome organization. Nevertheless, even the complete removal
of cohesin has surprisingly little impact on steady-state gene transcription and enhancer …
of cohesin has surprisingly little impact on steady-state gene transcription and enhancer …
The effects of work experience during higher education on labour market entry: learning by doing or an entry ticket?
Graduates from higher education often enter the labour market with a considerable amount
of work experience. Using German data, we address the question of whether early work …
of work experience. Using German data, we address the question of whether early work …
Cohesin-dependence of neuronal gene expression relates to chromatin loop length
Cohesin and CTCF are major drivers of 3D genome organization, but their role in neurons
is still emerging. Here, we show a prominent role for cohesin in the expression of genes that …
is still emerging. Here, we show a prominent role for cohesin in the expression of genes that …
Is forcing them worth the effort? Benefits of mandatory internships for graduates from diverse family backgrounds at labour market entry
Mandatory internships are implemented in higher education curricula in order to ease the
labour market integration of graduates. This article evaluates the utility of mandatory …
labour market integration of graduates. This article evaluates the utility of mandatory …
[HTML][HTML] Mouse screen reveals multiple new genes underlying mouse and human hearing loss
…, E Martelletti, L Preite, CC Lam, FD Weiss… - PLoS …, 2019 - journals.plos.org
Adult-onset hearing loss is very common, but we know little about the underlying molecular
pathogenesis impeding the development of therapies. We took a genetic approach to identify …
pathogenesis impeding the development of therapies. We took a genetic approach to identify …
From higher education to work patterns of labor market entry in Germany and the US
Comparative studies describing the transition from higher education to work have often
simplified the complex transition processes involved. In this paper we extend previous research …
simplified the complex transition processes involved. In this paper we extend previous research …
[HTML][HTML] Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin
Cornelia de Lange Syndrome (CdLS) is a human developmental disorder caused by mutations
that compromise the function of cohesin, a major regulator of 3D genome organization. …
that compromise the function of cohesin, a major regulator of 3D genome organization. …
Multisite assessment of reproducibility in high‐content cell migration imaging data
…, M van Erp, M Vullings, F Weiss… - Molecular Systems …, 2023 - embopress.org
High‐content image‐based cell phenotyping provides fundamental insights into a broad
variety of life science disciplines. Striving for accurate conclusions and meaningful impact …
variety of life science disciplines. Striving for accurate conclusions and meaningful impact …