Glucose homeostasis, regulated by glucose-dependent insulinotropic polypeptide (GIP),
glucagon-like peptide-1 (GLP-1) and glucagon (GCG) is critical to human health. Several multi-…

Adhesion G-protein-coupled receptors (aGPCRs) are important for organogenesis,
neurodevelopment, reproduction and other processes 1 , 2 , 3 , 4 , 5 – 6 . Many aGPCRs are …

Phosphorylation of G-protein-coupled receptors (GPCRs) by GPCR kinases (GRKs)
desensitizes G-protein signalling and promotes arrestin signalling, which is also modulated by …

Class B1 G protein-coupled receptors (GPCRs) play important roles in human physiology
and disease pathology. Using cryo-electron microscopy (cryo-EM) and X-ray crystallography, …

Growth hormone-releasing hormone (GHRH) regulates the secretion of growth hormone that
virtually controls metabolism and growth of every tissue through its binding to the cognate …

Abstracts Nanomaterials hold significant potential for industrial and biomedical application
these years. Therefore, the relationship between nanoparticles and neurodegenerative …

Glucagon-like peptides (GLP-1 and GLP-2) are two proglucagon-derived intestinal hormones
that mediate distinct physiological functions through two related receptors (GLP-1R and …

Glucose-dependent insulinotropic polypeptide (GIP) is a peptide hormone that exerts crucial
metabolic functions by binding and activating its cognate receptor, GIPR. As an important …

Graphene oxide (GO) has emerged as the worldwide promising candidate for biomedical
application, such as for drug delivery, bio‐sensing and anti‐cancer therapy. This study was …

Members of the melanocortin receptor (MCR) family that recognize different melanocortin
peptides mediate a broad spectrum of cellular processes including energy homeostasis, …