Multiple COVID-19 vaccines, representing diverse vaccine platforms, successfully protect
against symptomatic COVID-19 cases and deaths. Head-to-head comparisons of T cell, B cell, …

HIV-1 infection is characterized by generalized deregulation of the immune system, resulting
in increased chronic immune activation. However, some individuals called HIV controllers (…

Background Ongoing intra-host HIV-1 evolution has been shown in individuals that naturally
suppress the viremia to low levels (HIV controllers) by the analysis of the RNA in plasma …

Background: The mechanisms behind natural control of HIV replication are still unclear, and
several studies pointed that elite controllers (ECs) are a heterogeneous group. Methods: We …

Elite controllers (ECs) are rare individuals able to naturally control HIV-1 replication below
the detection limit of viral load (VL) commercial assays. It is unclear, however, whether ECs …

Background Some multifunctional cellular proteins, as the monocyte chemotactic protein-induced
protein 1 (ZC3H12A/MCPIP1) and the cyclin-dependent kinase inhibitor CDKN1A/p21, …

Objective: The aim of this study was to investigate the impact of intersubtype HIV-1
superinfection on viremia, reservoir reseeding, viral evolution and disease progression in HIV …

Chikungunya virus (CHIKV) is a mosquito-borne re-emerging viral infection that can cause
chronic chikungunya viral arthritic disease (CHIKVD), which is characterized by …

The analysis of the HIV-1 proviral dynamics after superinfection in the context of both natural
and antiretroviral therapy (ART)-mediated suppression could yield unique insights into …

O presente trabalho descreve o isolamento ea identificação de nove alcaloides indólicos
monoterpênicos das cascas das raízes e folhas de Tabernaemontana salzmannii (…