… Tina Vilsbøll associate professor and chief consultant endocrinologist , Mikkel Christensen
specialist registrar, Anders E Junker registrar, Filip K Knop associate professor and specialist …

The intestinal microbiota has been implicated in insulin resistance, although evidence
regarding causality in humans is scarce. We therefore studied the effect of lean donor (allogenic) …

Background & Aims Obesity has been associated with changes in the composition and
function of the intestinal microbiota. Modulation of the microbiota by antibiotics also alters bile …

To minimize the impact of antibiotics, gut microorganisms harbour and exchange antibiotics
resistance genes, collectively called their resistome. Using shotgun sequencing-based …

We aimed to investigate whether the reduced incretin effect observed in patients with type 2
diabetes is a primary event in the pathogenesis of type 2 diabetes or a consequence of the …

In healthy individuals, the incretin hormone glucagon-like peptide 1 (GLP1) potentiates
insulin release and suppresses glucagon secretion in response to the ingestion of nutrients. …

OBJECTIVE To evaluate the glucose dependency of glucose-dependent insulinotropic
polypeptide (GIP) effects on insulin and glucagon release in 10 healthy male subjects ([means ± …

Background We assessed the efficacy and safety of the oral glucagon-like peptide-1 analogue,
semaglutide 50 mg, taken once per day versus placebo for the treatment of overweight or …

Objective: Dietary fat is thought to stimulate release of incretin hormones via activation of
fatty acid receptors in the intestine. However, dietary fat (triacylglycerol) is digested to 2-…

OBJECTIVE Glucagon-like peptide 1 (GLP-1) exerts beneficial antidiabetic actions via effects
on pancreatic β- and α-cells. Previous studies have focused on the improvements in β-cell …