Drying techniques of probiotic bacteria as an important step towards the development of novel pharmabiotics

…, IJJ Claes, S Lebeer, F Kiekens - International journal of …, 2016 - Elsevier
The increasing knowledge about the human microbiome leads to the awareness of how
important probiotics can be for our health. Although further substantiation is required, it appears …

Improving folate (vitamin B9) stability in biofortified rice through metabolic engineering

…, J Van Daele, S Strobbe, F Kiekens… - Nature …, 2015 - nature.com
Biofortification of staple crops could help to alleviate micronutrient deficiencies in humans. We
show that folates in stored rice grains are unstable, which reduces the potential benefits of …

Interplay between Lactobacillus rhamnosus GG and Candida and the involvement of exopolysaccharides

…, S Kiekens, EFM Oerlemans, F Kiekens… - Microbial …, 2017 - Wiley Online Library
A number of clinical studies have shown protective effects of lactobacilli against Candida
species in the gastrointestinal tract, the urogenital tract and the oral cavity, while others did not …

Ordered mesoporous silica to enhance the bioavailability of poorly water-soluble drugs: Proof of concept in man

…, K Jolling, M De Gieter, B Bugarski, F Kiekens - European Journal of …, 2016 - Elsevier
Formulating poorly water soluble drugs using ordered mesoporous silica materials is an
emerging approach to tackle solubility-related bioavailability problems. The current study was …

[PDF][PDF] Lactobacilli have a niche in the human nose

…, AV Vroegop, A Verplaetse, T Van de Wiele, F Kiekens… - Cell reports, 2020 - cell.com
Although an increasing number of beneficial microbiome members are characterized for the
human gut and vagina, beneficial microbes are underexplored for the human upper …

Enhancing the viability of Lactobacillus rhamnosus GG after spray drying and during storage

…, D Vandenheuvel, T Henkens, S Kiekens… - International journal of …, 2017 - Elsevier
Increasing knowledge about the human microbiome has led to a growing awareness of the
potential of applying probiotics to improve our health. The pharmaceutical industry shows an …

[PDF][PDF] Selective targeting of skin pathobionts and inflammation with topically applied lactobacilli

…, S Wittouck, I De Boeck, CN Allonsius, F Kiekens… - Cell Reports …, 2022 - cell.com
Tailored skin microbiome modulation approaches with probiotics are highly challenging.
Here, we show that lactobacilli are underestimated members of the skin microbiota. We select …

Formation of aerobic granular sludge during the treatment of petrochemical wastewater

…, V Akkermans, D Daens, L Geuens, F Kiekens… - Bioresource …, 2017 - Elsevier
In this study, petrochemical wastewater from the port of Antwerp was used for the development
of aerobic granular sludge. Two different reactor setups were used, (1) a completely …

[HTML][HTML] Impact of a lactobacilli-containing gel on vulvovaginal candidosis and the vaginal microbiome

…, S Wittouck, MFL van Den Broek, S Wuyts, F Kiekens… - Scientific reports, 2020 - nature.com
Vulvovaginal candidosis (VVC) is a common condition with severe symptoms and high
recurrence rates. Probiotic lactobacilli are explored as alternatives to azole treatments. Although …

Mixed hemi/Ad-micelle sodium dodecyl sulfate-coated magnetic iron oxide nanoparticles for the efficient removal and trace determination of rhodamine-B and …

E Ranjbari, MR Hadjmohammadi, F Kiekens… - Analytical …, 2015 - ACS Publications
Mixed hemi/ad-micelle sodium dodecyl sulfate (SDS)-coated magnetic iron oxide
nanoparticles (MHAMS-MIONPs) were used as an efficient adsorbent for both removal and …