Poly(ethylene terephthalate) (PET) is one of the most abundantly produced synthetic polymers
and is accumulating in the environment at a staggering rate as discarded packaging and …

Plastics pollution represents a global environmental crisis. In response, microbes are
evolving the capacity to utilize synthetic polymers as carbon and energy sources. Recently, …

SARS-CoV-2 infection is controlled by the opening of the spike protein receptor binding
domain (RBD), which transitions from a glycan-shielded ‘down’ to an exposed ‘up’ state to bind …

Vaccines and drugs have helped reduce disease severity and blunt the spread of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). However, ongoing virus transmission…

Recent biochemical, biophysical, and genetic studies have shown that heparan sulfate, a
major component of the cellular glycocalyx, participates in infection of SARS-CoV-2 by …

Inspired by the role of cell-surface glycoproteins as coreceptors for pathogens, we report the
development of GlycoGrip: a glycopolymer-based lateral flow assay for detecting SARS-CoV…

Viral variants of concern continue to arise for SARS-CoV-2, potentially impacting both
methods for detection and mechanisms of action. Here, we investigate the effect of an evolving …

Prevention of infection and propagation of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is a high priority in the Coronavirus Disease 2019 (COVID-19) pandemic. …

Mucin-domain glycoproteins are densely O-glycosylated and play critical roles in a host of
biological functions. In particular, the T cell immunoglobulin and mucin-domain containing …

Gram-negative bacteria expressing class A β-lactamases pose a serious health threat due
to their ability to inactivate all β-lactam antibiotics. The acyl–enzyme intermediate is a central …