Fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) is a rare and recently
described entity associated with hereditary leiomyomatosis and RCC syndrome. FH-…

We assessed the frequency of programmed death-ligand 1 (PD-L1) expression by
immunohistochemistry (IHC) in a cohort of 522 sarcomas from 457 patients, incuding a subset of 46 …

… Fiona M Maclean… Fiona M Maclean … Fiona M Maclean …

Staging criteria for renal cell carcinoma differ from many other cancers, in that renal tumors
are often spherical with subtle, finger-like extensions into veins, renal sinus, or perinephric …

In this study we used the Illumina Infinium Methylation array to investigate in a cohort of
matched archival human tissue samples (n = 32) from 14 individuals with soft tissue sarcomas if …

Aims Amplification of the murine double minute‐2 (MDM2) gene, which is usually detected
with fluorescence in‐situ hybridisation (FISH), is the key driving event for atypical lipomatous …

ERG overexpression has been linked to acute myeloid leukemia/myeloid sarcoma (MS).
The aim of our study was to identify the frequency of ERG immunohistochemical (IHC) …

Background Newborn screening for cystic fibrosis (CF) relies on the measurement of
immunoreactive trypsinogen (IRT) originating from the pancreas. The Norfolk, Suffolk and …

Aims NTRK‐rearranged sarcomas are emerging as a distinct class of sarcomas of particular
importance in the era of targeted therapy. The aim of this study was to use array …

Aims Spermatocytic tumour (ST) is a rare testicular germ cell neoplasm with few confirmatory
biomarkers that can be challenging to diagnose. Like normal spermatogonia, STs are …