Pluripotent stem cell‐derived kidney organoids offer a promising solution to renal failure, yet
current organoid protocols often lead to off‐target cells and phenotypic alterations, …

Traditional synthetic covalent hydrogels lack the native tissue dynamics and hierarchical
fibrous structure found in the extracellular matrix (ECM). These dynamics and fibrous …

Differentiated kidney organoids from induced pluripotent stem cells hold promise as a treatment
for patients with kidney diseases. Before these organoids can be translated to the clinic, …

Synthetic hydrogels often lack the load‐bearing capacity and mechanical properties of
native biopolymers found in tissue, such as cartilage. In natural tissues, toughness is often …

Few synthetic hydrogels can mimic both the viscoelasticity and supramolecular fibrous
structure found in the naturally occurring extracellular matrix (ECM). Furthermore, the ability to …

Three-dimensional cell culture in engineered hydrogels is increasingly used in tissue
engineering and regenerative medicine. The transfer of nutrients, gases, and waste materials …

Conventional synthetic hydrogels often lack the load-bearing capacity and mechanical
properties of native biopolymers, such as cartilage. In some natural tissues, like cartilage, …

Current conventional cell culture methods for the expansion of cells to large quantities for
tissue engineering and regenerative medicine application relies on the use of enzymatic …

… As expected, Netrin-1 was ablated from the basal and floor plates of the ventral midbrain
and from mDA neurons in E13.5 Shh-Cre:Netrin-1fl/fl mice (Figures 4D, S5B, and S5C). Anal…

Here we report the development of a PLA/thermo-responsive (PDEGMA) blend 3D electrospun
fibre-based scaffold to create an enzymatic-free 3D cell culture platform for the expansion …