[HTML][HTML] IL-17RA in non-hematopoietic cells controls CXCL-1 and 5 critical to recruit neutrophils to the lung of mycobacteria-infected mice during the adaptive immune …

R Lombard, E Doz, F Carreras, M Epardaud, Y Le Vern… - PloS one, 2016 - journals.plos.org
During chronic infection with Mycobacterium tuberculosis (Mtb), bacilli multiplication is
constrained within lung granulomas until excessive inflammation destroys the lung. Neutrophils …

Mycobacteria-infected dendritic cells attract neutrophils that produce IL-10 and specifically shut down Th17 CD4 T cells through their IL-10 receptor

E Doz, R Lombard, F Carreras… - The Journal of …, 2013 - journals.aai.org
Neutrophils participate in the control of mycobacterial infection both by directly eliminating
bacilli and by interacting with macrophages and dendritic cells (DCs). Despite host defenses, …

[HTML][HTML] Experimental infection of cattle with Mycobacterium tuberculosis isolates shows the attenuation of the human tubercle bacillus for cattle

…, S Berg, A Whelan, S Holbert, F Carreras… - Scientific Reports, 2018 - nature.com
The Mycobacterium tuberculosis complex (MTBC) is the collective term given to the group of
bacteria that cause tuberculosis (TB) in mammals. It has been reported that M. tuberculosis …

Immunological responses and protective efficacy against Brucella melitensis induced by bp26 and omp31 B. melitensis Rev. 1 deletion mutants in sheep

…, M Grayon, N Vizcaino, A Peix, F Cortade, F Carreras… - Vaccine, 2007 - Elsevier
The commonly used live attenuated vaccine in ovine brucellosis prophylaxis is Brucella
melitensis Rev.1. This vaccine is known to induce antibody responses in vaccinated animals …

[HTML][HTML] Neutrophils encompass a regulatory subset suppressing T cells in apparently healthy cattle and mice

…, É Doz-Deblauwe, Y Le Vern, F Carreras… - Frontiers in …, 2021 - frontiersin.org
Neutrophils that reside in the bone marrow are swiftly recruited from circulating blood to
fight infections. For a long time, these first line defenders were considered as microbe killers. …

Allopatric combination of Fasciola hepatica and Lymnaea truncatula is more efficient than sympatric ones

N Gasnier, D Rondelaud, M Abrous, F Carreras… - International Journal for …, 2000 - Elsevier
Parasites are capable of rapid evolutionary changes relative to their hosts, due to short life
cycle, short generation time, and high fecundity. The direction of the evolution of parasite …

[HTML][HTML] CR3 engaged by PGL-I triggers Syk-calcineurin-NFATc to rewire the innate immune response in leprosy

É Doz-Deblauwe, F Carreras, A Arbues… - Frontiers in …, 2019 - frontiersin.org
Mycobacterium leprae, the causative agent of leprosy, is unique amongst human pathogens
in its capacity to produce the virulence factor phenolic glycolipid (PGL)-I. In addition to …

Vitamin D induced microbicidal activity against Mycobacterium bovis BCG is dependent on the synergistic activity of bovine peripheral blood cell populations

S Flores-Villalva, A Remot, F Carreras, N Winter… - Veterinary Immunology …, 2023 - Elsevier
A growing appreciation is emerging of the beneficial role of vitamin D for health and
resistance against infectious diseases, including tuberculosis. However, research has …

[HTML][HTML] Mycobacterial Infection of Precision-Cut Lung Slices Reveals Type 1 Interferon Pathway Is Locally Induced by Mycobacterium bovis but Not M. tuberculosis …

A Remot, F Carreras, A Coupé… - Frontiers in veterinary …, 2021 - frontiersin.org
Tuberculosis exacts a terrible toll on human and animal health. While Mycobacterium tuberculosis
(Mtb) is restricted to humans, Mycobacterium bovis (Mb) is present in a large range of …

[HTML][HTML] The C3HeB/FeJ mouse model recapitulates the hallmark of bovine tuberculosis lung lesions following Mycobacterium bovis aerogenous infection

M Bouté, F Carreras, C Rossignol, E Doz, N Winter… - Veterinary …, 2017 - Springer
Achieving the control of bovine tuberculosis (bTB) would require the discovery of an efficient
combined immunodiagnostic and vaccine strategy. Since in vivo experiments on cattle are …