We describe a collection of P-element insertions that have considerable utility for generating
custom chromosomal aberrations in Drosophila melanogaster. We have mobilized a pair of …

Upon apoptotic stimuli, epithelial cells compensate the gaps left by dead cells by activating
proliferation. This has led to the proposal that dying cells signal to surrounding living cells to …

Regeneration and tissue repair allow damaged or lost body parts to be replaced. After injury
or fragmentation of Drosophila imaginal discs, regeneration leads to the development of …

One of the main topics in regeneration biology is the nature of the early signals that trigger
the damage response. Recent advances in Drosophila point to the MAP3 kinase Ask1 as a …

Many animals display a capacity to regenerate tissues or even a complete body. One of the
main goals of regenerative biology is to identify the genes and genetic networks necessary …

Highlights • Drosophila imaginal discs are capable of regeneration after damage. • Genetic
tools enable specific regions of imaginal discs to be ablated in situ. • Reactive oxygen species…

We describe a second-generation deficiency kit for Drosophila melanogaster composed of
molecularly mapped deletions on an isogenic background, covering ∼77% of the Release …

We have examined wound healing during regeneration of Drosophila wing imaginal discs
fragments by confocal microscopy and assessed the role of components of the JNK pathway …

In selenoproteins, incorporation of the amino acid selenocysteine is specified by the UGA
codon, usually a stop signal. The alternative decoding of UGA is conferred by an mRNA …

UEV proteins are enzymatically inactive variants of the E2 ubiquitin-conjugating enzymes
that regulate noncanonical elongation of ubiquitin chains. In Saccharomyces cerevisiae, UEV …