User profiles for Florian Hinzpeter
Florian HinzpeterTechnical University Munich Verified email at tum.de Cited by 133 |
Regulation of reaction fluxes via enzyme sequestration and co-clustering
F Hinzpeter, F Tostevin… - Journal of The Royal …, 2019 - royalsocietypublishing.org
Experimental observations suggest that cells change the intracellular localization of key
enzymes to regulate the reaction fluxes in enzymatic networks. In particular, cells appear to use …
enzymes to regulate the reaction fluxes in enzymatic networks. In particular, cells appear to use …
[PDF][PDF] Optimal compartmentalization strategies for metabolic microcompartments
F Hinzpeter, U Gerland, F Tostevin - Biophysical Journal, 2017 - cell.com
Intracellular compartmentalization of cooperating enzymes is a strategy that is frequently
used by cells. Segregation of enzymes that catalyze sequential reactions can alleviate …
used by cells. Segregation of enzymes that catalyze sequential reactions can alleviate …
Trade-offs and design principles in the spatial organization of catalytic particles
F Hinzpeter, F Tostevin, A Buchner, U Gerland - Nature Physics, 2022 - nature.com
Catalytic particles are spatially organized in a number of biological systems across different
length scales, from enzyme complexes to metabolically coupled cells. Despite operating on …
length scales, from enzyme complexes to metabolically coupled cells. Despite operating on …
Optimization of collective enzyme activity via spatial localization
A Buchner, F Tostevin, F Hinzpeter… - The Journal of chemical …, 2013 - pubs.aip.org
The spatial organization of enzymes often plays a crucial role in the functionality and
efficiency of enzymatic pathways. To fully understand the design and operation of enzymatic …
efficiency of enzymatic pathways. To fully understand the design and operation of enzymatic …
[PDF][PDF] Kinetics of Spatially Organized Biochemical Reactions
F Hinzpeter - 2018 - core.ac.uk
The metabolism of all living organism relies on the catalytic action of enzymes. To achieve
complex biochemical transformations, sets of enzymes work together in so-called metabolic …
complex biochemical transformations, sets of enzymes work together in so-called metabolic …
(TORC) ing up purine biosynthesis
Proliferating cells must coordinate their metabolic activities to meet the bioenergetic and
biosynthetic demands of anabolic growth. Rapidly growing cells—such as cancer cells—…
biosynthetic demands of anabolic growth. Rapidly growing cells—such as cancer cells—…
Prevention of interferon-alpha associated depression in psychiatric risk patients with chronic hepatitis C
…, M Schwaiger, AS Garkisch, M Pich, A Hinzpeter… - Journal of …, 2005 - Elsevier
Background/Aims: Interferon-alpha (IFN-α) induced depression is a major limitation for the
treatment of chronic hepatitis C, especially for patients with psychiatric disorders. We …
treatment of chronic hepatitis C, especially for patients with psychiatric disorders. We …
[PDF][PDF] Dubrovnik-Croatia
N Pedemonte, A Hinzpeter, C Ehre - 2023 - ecfs.eu
Basic scientific discovery is critical to our understanding of CF. New therapies targeting the
basic defect have been an extraordinary achievement coming from basic scientific research. …
basic defect have been an extraordinary achievement coming from basic scientific research. …
CT in transcatheter-delivered treatment of valvular heart disease
PN Rudzinski, JA Leipsic, UJ Schoepf, D Dudek… - Radiology, 2022 - pubs.rsna.org
Minimally invasive strategies to treat valvular heart disease have emerged over the past 2
decades. The use of transcatheter aortic valve replacement in the treatment of severe aortic …
decades. The use of transcatheter aortic valve replacement in the treatment of severe aortic …
[HTML][HTML] Observation of sensible and latent heat flux profiles with lidar
A Behrendt, V Wulfmeyer, C Senff… - Atmospheric …, 2020 - amt.copernicus.org
We present the first measurement of the sensible heat flux (H) profile in the convective
boundary layer (CBL) derived from the covariance of collocated vertical-pointing temperature …
boundary layer (CBL) derived from the covariance of collocated vertical-pointing temperature …