User profiles for Florian Mair
 | Florian MairETH Zurich, Switzerland Verified email at biol.ethz.ch Cited by 5133 |
[PDF][PDF] The cytokine GM-CSF drives the inflammatory signature of CCR2+ monocytes and licenses autoimmunity
…, M Lanzinger, FJ Hartmann, B Schreiner, F Mair… - Immunity, 2015 - cell.com
Granulocyte-macrophage colony-stimulating factor (GM-CSF) has emerged as a crucial
cytokine produced by auto-reactive T helper (Th) cells that initiate tissue inflammation. Multiple …
cytokine produced by auto-reactive T helper (Th) cells that initiate tissue inflammation. Multiple …
Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline
The pathology of Alzheimer's disease has an inflammatory component that is characterized
by upregulation of proinflammatory cytokines, particularly in response to amyloid-β (Aβ). …
by upregulation of proinflammatory cytokines, particularly in response to amyloid-β (Aβ). …
High-dimensional analysis of the murine myeloid cell system
Advances in cell-fate mapping have revealed the complexity in phenotype, ontogeny and
tissue distribution of the mammalian myeloid system. To capture this phenotypic diversity, we …
tissue distribution of the mammalian myeloid system. To capture this phenotypic diversity, we …
The end of gating? An introduction to automated analysis of high dimensional cytometry data
Ever since its invention half a century ago, flow cytometry has been a major tool for single‐cell
analysis, fueling advances in our understanding of a variety of complex cellular systems, …
analysis, fueling advances in our understanding of a variety of complex cellular systems, …
[HTML][HTML] NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
Inflammasomes form as the result of the intracellular presence of danger-associated
molecular patterns and mediate the release of active IL-1β, which influences a variety of …
molecular patterns and mediate the release of active IL-1β, which influences a variety of …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
…, L Maggi, MK Maini, F Mair… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …
performing flow cytometry experiments and includes comprehensive sections describing …
IL‐23: one cytokine in control of autoimmunity
During the past decade, it has been firmly established that IL ‐23 is essential for disease
development in several models of autoimmune disease, including psoriatic skin inflammation, …
development in several models of autoimmune disease, including psoriatic skin inflammation, …
[HTML][HTML] Extricating human tumour immune alterations from tissue inflammation
Immunotherapies have achieved remarkable successes in the treatment of cancer, but major
challenges remain 1 , 2 . An inherent weakness of current treatment approaches is that …
challenges remain 1 , 2 . An inherent weakness of current treatment approaches is that …
[PDF][PDF] Dysregulation of the cytokine GM-CSF induces spontaneous phagocyte invasion and immunopathology in the central nervous system
Chronic inflammatory diseases are influenced by dysregulation of cytokines. Among them,
granulocyte macrophage colony stimulating factor (GM-CSF) is crucial for the pathogenic …
granulocyte macrophage colony stimulating factor (GM-CSF) is crucial for the pathogenic …
An updated guide for the perplexed: cytometry in the high-dimensional era
High-dimensional cytometry experiments measuring 20–50 cellular markers have become
routine in many laboratories. The increased complexity of these datasets requires added rigor …
routine in many laboratories. The increased complexity of these datasets requires added rigor …