[HTML][HTML] Enterococcus faecalis alters endo-lysosomal trafficking to replicate and persist within mammalian cells

RAG da Silva, WH Tay, FK Ho, FR Tanoto… - PLoS …, 2022 - journals.plos.org
Enterococcus faecalis is a frequent opportunistic pathogen of wounds, whose infections are
associated with biofilm formation, persistence, and recalcitrance toward treatment. We have …

[HTML][HTML] Escherichia coli BarA-UvrY regulates the pks island and kills Staphylococci via the genotoxin colibactin during interspecies competition

JJ Wong, FK Ho, PY Choo, KKL Chong, CMB Ho… - PLoS …, 2022 - journals.plos.org
Wound infections are often polymicrobial in nature, biofilm associated and therefore tolerant
to antibiotic therapy, and associated with delayed healing. Escherichia coli and …

[HTML][HTML] Cellular chaining influences biofilm formation and structure in group A Streptococcus

A Matysik, FK Ho, AQL Tan, A Vajjala, KA Kline - Biofilm, 2020 - Elsevier
Group A Streptococcal (GAS) biofilm formation is an important pathological feature contributing
to the antibiotic tolerance and progression of various GAS infections. Although a number …

Enterococcus faecalis persists and replicates within epithelial cells in vitro and in vivo during wound infection

WH Tay, RAG da Silva, FK Ho, KKL Chong, A Ludwig… - bioRxiv, 2021 - biorxiv.org
Enterococcus faecalis is a frequent opportunistic pathogen of wounds, whose infections are
associated with biofilm formation, persistence, and recalcitrance toward treatment. We have …

Escherichia coli BarA-UvrY regulates the pks island and kills Staphylococci via the genotoxin colibactin

JJ Wong, KKL Chong, FK Ho, CM Benjamin Ho… - bioRxiv, 2021 - biorxiv.org
Wound infections are often polymicrobial in nature and are associated with poor disease
prognoses. Escherichia coli and Staphylococcus aureus are among the top five most cultured …

Characterization of zebrafish IKK2 mutants generated by zinc finger nucleases

FK Ho - 2014 - dr.ntu.edu.sg
IκB kinase β (IKK2/IKKβ) is known as a master regulator of NF-κB signaling, which mediates
stress, immune and inflammatory responses. Unfortunately, embryonic lethality in IKK2-…

Oncologist-led BRCA counselling improves access to cancer genetic testing in middle-income Asian country, with no significant impact on psychosocial outcomes

…, S Tayib, N Cheah, BK Lim, CK Fong, YC Foo… - Journal of medical …, 2022 - jmg.bmj.com
Background Identifying patients with BRCA mutations is clinically important to inform on the
potential response to treatment and for risk management of patients and their relatives. …

Debating integration in Singapore, deepening the variegations of the Chinese diaspora

ELE Ho, FY Foo - Contemporary Chinese Diasporas, 2017 - Springer
This chapter focuses on integration debates concerning the recent immigration of mainland
Chinese migrants to Singapore. While the Singaporean state emphasizes the importance of …

Interaction graph mining for protein complexes using local clique merging

XL Li, CS Foo, SH Tan, SK Ng - Genome Informatics, 2005 - jstage.jst.go.jp
While recent technological advances have made available large datasets of
experimentallydetected pairwise protein-protein interactions, there is still a lack of experimentally-…

Discovering protein complexes in dense reliable neighborhoods of protein interaction networks

XL Li, CS Foo, SK Ng - Computational Systems Bioinformatics …, 2007 - World Scientific
Multiprotein complexes play central roles in many cellular pathways. Although many high-throughput
experimental techniques have already enabled systematic screening of pairwise …