Heart failure with preserved ejection fraction (HFpEF) involves multiple pathophysiological
mechanisms, which result in the heterogeneous phenotypes that are evident clinically, and …

Aims Remote monitoring of patients with physiological data derived from cardiac implanted
electronic devices (CIEDs) offers potential to reconfigure clinical services. The ‘Heart Failure …

Background Heart failure (HF) is a chronic disease associated with a significant burden to
patients, families, and health services. The diagnosis of HF can be easily missed owing to …

Aims To examine the utility of 18 F-fluorodeoxyglucose positron emission tomography/computed
tomography ( 18 F-FDG PET/CT) in the early diagnosis of cardiac implantable …

Objectives Recently published clinical guidelines recommend cardiac resynchronisation
therapy (CRT) for patients with heart failure (HF) with reduced LVEF and non-left bundle branch …

Aims To determine if remotely monitored physiological data from cardiac implantable electronic
devices (CIEDs) can be used to identify patients at high risk of mortality. Methods and …

Background Heart failure with preserved ejection fraction is increasing in prevalence and is
associated with a high symptom burden and functional impairment, especially in persons …

In heart failure with preserved ejection fraction (HFpEF), the occurrence of myocardial fibrosis
is associated with adverse outcome. Whether pirfenidone, an oral antifibrotic agent without …

In the STEP-HFpEF trial, semaglutide improved symptoms, physical limitations and exercise
function and reduced body weight in patients with obesity phenotype of heart failure and …

Background Obesity and type 2 diabetes are prevalent in patients with heart failure with
preserved ejection fraction and are characterized by a high symptom burden. No approved …