Gut microbiota is involved in the development of several chronic diseases, including diabetes,
obesity, and cancer, through its interactions with the host organs. It has been suggested …

Ageing causes a progressive decline in skeletal muscle mass that may lead to decreased
strength and functionality. The term sarcopenia is especially used to characterise this geriatric …

A paradox is a seemingly absurd or impossible concept, proposition, or theory that is often
difficult to understand or explain, sometimes apparently self-contradictory, and yet ultimately …

More than 50% of patients with advanced stages of colon cancer suffer from progressive
loss of skeletal muscle, called cachexia, resulting in reduced quality of life and shortened …

Epidemiological data indicate that physical inactivity, a main factor of global energetic
imbalance, is involved in the worldwide epidemic of obesity and metabolic disorders such as …

Low mitochondriogenesis is critical to explain loss of muscle function in aging and in the
development of frailty. The aim of this work was to explain the mechanism by which …

In the literature, the terms physical inactivity and immobilization are largely used as synonyms.
The present review emphasizes the need to establish a clear distinction between these …

Gut microbiota, a major contributor to human health, is influenced by physical activity and
diet, and displays a functional cross-talk with skeletal muscle. Conversely, few data are …

Bedridden patients in intensive care unit or after surgery intervention commonly develop
skeletal muscle weakness. The latter is promoted by a variety of prolonged hospitalization-…

The objective of the present study was to determine the effects of dry immersion, an innovative
ground-based human model of simulated microgravity and extreme physical inactivity, on …