Tumors may be initiated and maintained by a cellular subcomponent that displays stem cell
properties. We have used the expression of aldehyde dehydrogenase as assessed by the …

Purpose: To examine the role of cancer stem cells (CSC) in mediating metastasis in
inflammatory breast cancer (IBC) and the association of these cells with patient outcome in this …

The basal molecular subtype of breast cancer (BC) is defined by the mRNA expression
pattern of an intrinsic ∼500‐gene set. It is the most homogeneous subtype in transcriptional …

Metastasis is the main cause of death for patients with breast cancer. Many studies have
characterized the genomic landscape of breast cancer during its early stages. However, there is …

Expression of programmed cell death receptor ligand 1 (PDL1) has been scarcely studied
in breast cancer. Recently PD1/PDL1-inhibitors have shown promising results in different …

Triple-negative breast cancer (TNBC) remains an unmet medical challenge. We investigated
metabolic dysregulation in TNBCs by using our multi-omics database (n = 465, the largest …

Basal and luminal are two molecular subtypes of breast cancer with opposite histoclinical
features. We report a combined, high-resolution analysis of genome copy number and gene …

Background The effect of imatinib discontinuation on progression-free survival and overall
survival in long-lasting responders with advanced gastrointestinal stromal tumours (GIST) is …

Metabolic reprogramming is a hallmark of cancer. However, systematic characterizations of
metabolites in triple-negative breast cancer (TNBC) are still lacking. Our study profiled the …

Background Sarcomas are rare but aggressive diseases. Specialized multidisciplinary
management is not implemented for all patients in most countries. We investigated the impact of a …