Inflammatory bowel diseases are chronic gastrointestinal inflammatory disorders that affect
millions of people worldwide. Genome-wide association studies have identified 200 …

GWAS have identified >200 risk loci for Inflammatory Bowel Disease (IBD). The majority of
disease associations are known to be driven by regulatory variants. To identify the putative …

Background & Aims A few rare monogenic primary immunodeficiencies (PIDs) are
characterized by chronic intestinal inflammation that resembles Crohn’s disease (CD). We …

Inflammatory bowel disease (IBD) is a chronic gastrointestinal inflammatory disorder that
affects millions worldwide. Genome-wide association studies (GWAS) have identified 200 IBD-…

The host immune system plays an critical role in maintaining homeostasis with resident
microbial communities, therefore ensuring that the complex symbiotic relationship is maintained. …

The host immune system plays an critical role in maintaining homeostasis with resident
microbial communities, therefore ensuring that the complex symbiotic relationship is maintained. …

Lifetime prevalence of inflammatory bowel disease (IBD) is reaching an alarming rate of >1/400
in industrialized societies. Improved understanding of disease pathogenesis is essential …

Genome Wide Association Studies (GWAS) have identified at least 68 loci involved in
megakaryopoiesis and platelet formation. As for all GWAS, identified risk loci span hundreds of …

Background/Purpose: Immune-mediated inflammatory disorders (IMIDs) share many genetic
risk factors. Pleiotropy may exist at different levels and most of the underlying mechanisms …

Cette thèse est consacrée à l'étude de la classe des systèmes hyperboliques partiellement
dissipatifs satisfaisant la condition de stabilité de Shizuta-Kawashima (souvent appelée "…