We reviewed evidence of the clinical implications and burden of malaria in pregnancy. Most
studies come from sub-Saharan Africa, where approximately 25 million pregnant women are …

Artemisinin-based combination treatments (ACTs) are now generally accepted as the best
treatments for uncomplicated falciparum malaria. They are rapidly and reliably effective. …

Most pregnant women at risk of for infection with Plasmodium vivax live in the Asia-Pacific
region. However, malaria in pregnancy is not recognised as a priority by many governments, …

Background Artemisinin-based combination therapies are the recommended first-line treatments
of falciparum malaria in all countries with endemic disease. There are recent concerns …

Background Artemisinin-resistant falciparum malaria has arisen in western Cambodia. A
concerted international effort is underway to contain artemisinin-resistant Plasmodium …

Background The borders of Thailand harbour the world's most multidrug resistant Plasmodium
falciparum parasites. In 1984 mefloquine was introduced as treatment for uncomplicated …

Women are at increased risk from malaria during pregnancy, and, for unknown reasons, this
risk is greatest during the first pregnancy 1 . Plasmodium falciparum, the most virulent of the …

Viewpoint reduced mefloquine sensitivity is lessened substantially. 8 Second, the artemisinin
derivatives decrease gametocyte carriage by roughly 90%. 9 Recrudescent (ie, resistant) …

Here we present molecular evidence demonstrating that malaria parasites bearing high-level
pyrimethamine resistance originally arrived in Africa from southeast Asia. The resistance …

We describe an analysis of genome variation in 825 P. falciparum samples from Asia and
Africa that identifies an unusual pattern of parasite population structure at the epicenter of …