User profiles for Francesca Perrone
Francesca PerroneUniversity of Cambridge Verified email at cam.ac.uk Cited by 742 |
[HTML][HTML] Cells of the human intestinal tract mapped across space and time
…, L Bolt, SF Vieira, L Mamanova, N Huang, F Perrone… - Nature, 2021 - nature.com
The cellular landscape of the human intestinal tract is dynamic throughout life, developing
in utero and changing in response to functional requirements and environmental exposures. …
in utero and changing in response to functional requirements and environmental exposures. …
[HTML][HTML] Potential applications of nanocellulose-containing materials in the biomedical field
Because of its high biocompatibility, bio-degradability, low-cost and easy availability, cellulose
finds application in disparate areas of research. Here we focus our attention on the most …
finds application in disparate areas of research. Here we focus our attention on the most …
A roadmap for the human gut cell atlas
The number of studies investigating the human gastrointestinal tract using various single-cell
profiling methods has increased substantially in the past few years. Although this increase …
profiling methods has increased substantially in the past few years. Although this increase …
[HTML][HTML] MicroRNA let-7g acts as tumor suppressor and predictive biomarker for chemoresistance in human epithelial ovarian cancer
Remarkable deregulation of microRNAs has been demonstrated in epithelial ovarian cancer
(EOC). In particular, some of the let-7 miRNA family members have been proposed as …
(EOC). In particular, some of the let-7 miRNA family members have been proposed as …
[HTML][HTML] Biobanking of human gut organoids for translational research
F Perrone, M Zilbauer - Experimental & Molecular Medicine, 2021 - nature.com
The development of human organoid culture models has led to unprecedented opportunities
to generate self-organizing, three-dimensional miniature organs that closely mimic in vivo …
to generate self-organizing, three-dimensional miniature organs that closely mimic in vivo …
Recent advances in smart biotechnology: Hydrogels and nanocarriers for tailored bioactive molecules depot
Over the past ten years, the global biopharmaceutical market has remarkably grown, with
ten over the top twenty worldwide high performance medical treatment sales being biologics. …
ten over the top twenty worldwide high performance medical treatment sales being biologics. …
A functional genetic toolbox for human tissue-derived organoids
Human organoid systems recapitulate key features of organs offering platforms for modelling
developmental biology and disease. Tissue-derived organoids have been widely used to …
developmental biology and disease. Tissue-derived organoids have been widely used to …
Gastrointestinal symptoms in patients with asthma
C Caffarelli, FM Deriu, V Terzi, F Perrone… - Archives of disease in …, 2000 - adc.bmj.com
AIMS Minor gastrointestinal abnormalities have been reported in children with asthma, but
the prevalence of gastrointestinal symptoms in these children has not been studied. …
the prevalence of gastrointestinal symptoms in these children has not been studied. …
Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer
Given the lack of effective treatments for Hepatocellular carcinoma (HCC), the development
of novel therapeutic approaches is very urgent. Here, siRNAs were delivered to HCC cells …
of novel therapeutic approaches is very urgent. Here, siRNAs were delivered to HCC cells …
[HTML][HTML] Efficient genetic editing of human intestinal organoids using ribonucleoprotein-based CRISPR
…, R Kemp, A Smith, F Perrone… - Disease Models & …, 2023 - journals.biologists.com
Organoids, combined with genetic editing strategies, have the potential to offer rapid and
efficient investigation of gene function in many models of human disease. However, to date, the …
efficient investigation of gene function in many models of human disease. However, to date, the …