Babelomics has been running for more than one decade offering a user-friendly interface
for the functional analysis of gene expression and genomic data. Here we present its fifth …

Understanding the aspects of the cell functionality that account for disease or drug action
mechanisms is a main challenge for precision medicine. Here we propose a new method that …

Background Understanding the aspects of the cell functionality that account for disease or
drug action mechanisms is one of the main challenges in the analysis of genomic data and is …

Whole-exome sequencing has become a fundamental tool for the discovery of disease-related
genes of familial diseases and the identification of somatic driver variants in cancer. …

Many complex traits, as drug response, are associated with changes in biological pathways
rather than being caused by single gene alterations. Here, a predictive framework is …

In spite of the increasing availability of genomic and transcriptomic data, there is still a gap
between the detection of perturbations in gene expression and the understanding of their …

Cancer is driven by genomic alterations, but the processes causing this disease are largely
performed by proteins. However, proteins are harder and more expensive to measure than …

During the past years, the advances in high-throughput technologies have produced an
unprecedented growth in the number and size of repositories and databases storing relevant …

The discovery of actionable targets is crucial for targeted therapies and is also a constituent
part of the drug discovery process. The success of an intervention over a target depends …

The massive use of Next-Generation Sequencing (NGS) technologies is uncovering an
unexpected amount of variability. The functional characterization of such variability, particularly …