Understanding the endogenous repair capacity of spinal cord is pivotal to develop strategies
to improve it. Here we design a paradigm of spinal cord lesion in the dorsal column using a …

Debarbieux, Franck, Jennifer Brunton, and Serge Charpak. Effect of bicuculline on thalamic
activity: a direct blockade of I AHP in reticularis neurons. J. Neurophysiol. 79: 2911–2918, …

Key points • Chronic in vivo imaging of cellular interactions within the adult spinal cord with
subcellular resolution is important for understanding cellular physiology and disease …

Drug delivery to the central nervous system is hindered by the presence of physiological
barriers such as the blood–brain barrier. To accomplish the task of nutrient transport, the brain …

In both multiple sclerosis and its model experimental autoimmune encephalomyelitis (EAE),
the extent of resident microglia activation and infiltration of monocyte-derived cells to the …

The majority of intravital studies on brain tumor in living animal so far rely on dual color
imaging. We describe here a multiphoton imaging protocol to dynamically characterize the …

Inflammatory cells, an integral component of tumor evolution, are present in Glioblastomas
multiforme (GBM). To address the cellular basis and dynamics of the inflammatory …

We previously reported that embryonic motor cortical neurons transplanted immediately
after lesions in the adult mouse motor cortex restored damaged motor cortical pathways. A …

Key points • Inflammatory cells such as myelomonocytic cells are key players in the
progression and recovery from spinal cord injury (SCI). • However, the precise spatiotemporal …

Myelin around axons is currently widely studied by structural analyses and large-scale
imaging techniques, with the goal to decipher its critical role in neuronal protection. Although …