The ongoing monkeypox virus (MPXV) outbreak is the largest ever recorded outside of Africa.
We isolated and sequenced a virus from the first clinical MPXV case diagnosed in France (…

Genome dynamics are intimately linked to the regulation of gene expression, the most
fundamental mechanism in biology, yet we still do not know whether the very process of …

Chromosome breakage is a major threat to genome integrity. The most accurate way to repair
DNA double strand breaks (DSB) is homologous recombination (HR) with an intact copy of …

The yeast telomerase holoenzyme, which adds telomeric repeats at the chromosome ends,
is composed of the TLC1 RNA and the associated proteins Est1, Est2 and Est3. To study the …

The telomerase, which is composed of both protein and RNA, maintains genome stability by
replenishing telomeric repeats at the ends of chromosomes. Here, we use live-cell imaging …

Transcripts containing expanded CNG repeats, which are found in several neuromuscular
diseases, are not exported from the nucleus and aggregate as ribonuclear inclusions by an …

Human cytomegalovirus (HCMV) induces latent lifelong infections in all human populations.
Between 30% and nearly 100% of individuals are affected depending on the geographic …

Adenoviruses are DNA viruses with a lytic infection cycle. Following the fate of incoming as
well as recently replicated genomes during infections is a challenge. In this study, we used …

… in the form of salaries for F Gallardo, but did not have any … the authors' results, F Gallardo,
chief executive officer at … in the form of salaries for F Gallardo, but did not have any additional …

Telomere maintenance in eukaryotes is linked to cellular proliferation capacity. The telomerase
holoenzyme, which maintains telomere length, is a central actor in this process and its …