OBJECTIVE: To measure in vivo neurochemical changes in the caudate nucleus in
pediatric obsessive-compulsive disorder (OCD) before and after treatment. METHOD: Single-voxel …

Alterations in white matter (WM) microstructure have been implicated in the pathophysiology
of major depressive disorder (MDD). However, previous findings have been inconsistent, …

BACKGROUND: Abnormalities in the amygdala and hippocampus have been implicated in
the pathogenesis of major depressive disorder (MDD). To our knowledge, no prior study has …

Background Abnormalities in limbic structures have been implicated in major depressive
disorder (MDD). Although MDD is as common in adolescence as in adulthood, few studies …

Major depressive disorder (MDD) is associated with an increased risk of brain atrophy,
aging-related diseases, and mortality. We examined potential advanced brain aging in adult …

Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with cognitive,
motor, and emotional symptoms. The thalamus and basal ganglia form circuits with the cortex …

A key objective in the field of translational psychiatry over the past few decades has been to
identify the brain correlates of major depressive disorder (MDD). Identifying measurable …

Emerging evidence suggests that obesity impacts brain physiology at multiple levels. Here
we aimed to clarify the relationship between obesity and brain structure using structural MRI (…

Objective To characterize white matter alterations in children with isolated or concurrent
developmental coordination disorder and/or attention-deficit/hyperactivity disorder (ADHD) …

BACKGROUND: The frontal–striatal pathway has been previously implicated in the
neuropathology of attention-deficit/hyperactivity disorder (ADHD). Hence, we used proton magnetic …