Background Evidence suggests that the PfKelch13 mutations that confer artemisinin
resistance in falciparum malaria have multiple independent origins across the Greater Mekong …

Background Emergence of artemisinin resistance in southeast Asia poses a serious threat
to the global control of Plasmodium falciparum malaria. Discovery of the K13 marker has …

This guideline aimed to advance current understandings regarding the diagnosis, prevention
and therapeutic interventions for ankle sprains by updating the existing guideline and …

Malaria parasites (Plasmodium falciparum) provide an excellent system in which to study the
genomic effects of strong selection in a recombining eukaryote because the rapid spread of …

Background Artemisinin and partner-drug resistance in Plasmodium falciparum are major
threats to malaria control and elimination. Triple artemisinin-based combination therapies (…

Artesunate is a key antimalarial drug in the treatment of multidrug-resistant Plasmodium
falciparum malaria in southeast Asia. We investigated the distribution of counterfeit artesunate …

Background Artemisinin-combination therapy (ACT) is recommended as first-line treatment
of falciparum malaria throughout the world, and fixed-dose combinations are preferred by …

Parasite clearance data from 18,699 patients with falciparum malaria treated with an artemisinin
derivative in areas of low (n = 14,539), moderate (n = 2077), and high (n = 2083) levels …

Background The Greater Mekong subregion is a recurrent source of antimalarial drug
resistance in Plasmodium falciparum malaria. This study aimed to characterise the extent and …

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