Oligonucleotide probe arrays have enabled massively parallel analysis of gene expression
levels from a single cDNA sample. Application of microarray technology to analyzing …

We describe an efficient, accurate and robust whole-genome genotyping (WGG) assay
based on a two-color, single-base extension (SBE), single-nucleotide polymorphism (SNP)-…

To resolve cellular heterogeneity, we developed a combinatorial indexing strategy to profile
the transcriptomes of single cells or nuclei, termed sci-RNA-seq (single-cell combinatorial …

We have developed a randomly ordered fiber-optic gene array for rapid, parallel detection
of unlabeled DNA targets with surface immobilized molecular beacons (MB) that undergo a …

Technical advances have enabled the collection of genome and transcriptome data sets
with single-cell resolution. However, single-cell characterization of the epigenome has …

We present single-cell combinatorial indexed Hi-C (sciHi-C), a method that applies
combinatorial cellular indexing to chromosome conformation capture. In this proof of concept, we …

We have developed a flexible, accurate and highly multiplexed SNP genotyping assay for
high-throughput genetic analysis of large populations on a bead array platform. The novel …

INTRODUCTION A reference atlas of human cell types is a major goal for the field. Here, we
set out to generate single-cell atlases of both gene expression (this study) and chromatin …

The synthesis is described of a series of calix [4] arenes with three different sensitizer
chromophores (“antenna”) attachedto the lower rim via a short spacer. In the Eu3+ and Tb3+ …

Although we can increasingly measure transcription, chromatin, methylation, and other
aspects of molecular biology at single-cell resolution, most assays survey only one aspect of …