The landmark HIV Prevention Trials Network (HPTN) 052 trial in HIV-discordant couples
demonstrated unequivocally that treatment with antiretroviral therapy (ART) substantially lowers …

HIV/AIDS is a leading cause of disease burden in sub-Saharan Africa. Existing evidence
has demonstrated that there is substantial local variation in the prevalence of HIV; however, …

Physical access to health care affects a large array of health outcomes, yet meaningfully
estimating physical access remains elusive in many developing country contexts where …

Background South Africa contains more than one in seven of the world's HIV-positive
population. Knowledge of local variation in levels of HIV infection is important for prioritization of …

Background Primary malaria prevention on a large scale depends on two vector control
interventions: indoor residual spraying (IRS) and insecticide‐treated mosquito nets (ITNs). …

Background Climate change is likely to affect transmission of vector-borne diseases such as
malaria. We quantitatively estimated current malaria exposure and assesed the potential …

The progression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic in Africa has so far been heterogeneous, and the full impact is not yet well understood…

The health and demography of the South African population has been undergoing
substantial changes as a result of the rapidly progressing HIV epidemic. Researchers at the …

Background Universal antiretroviral therapy (ART), as per the 2015 WHO recommendations,
might reduce population HIV incidence. We investigated the effect of universal test and treat …

Africa is generally held to be in crisis, and the quality of life for the majority of the continent's
inhabitants has been declining in both relative and absolute terms. In addition, the majority …