User profiles for Frank W. Albert

Frank W. Albert

University of Minnesota
Verified email at umn.edu
Cited by 4842

The evolution of gene expression levels in mammalian organs

…, A Liechti, A Aximu-Petri, M Kircher, FW Albert… - Nature, 2011 - nature.com
Abstract Changes in gene expression are thought to underlie many of the phenotypic
differences between species. However, large-scale analyses of gene expression evolution were …

[HTML][HTML] The role of regulatory variation in complex traits and disease

FW Albert, L Kruglyak - Nature Reviews Genetics, 2015 - nature.com
We are in a phase of unprecedented progress in identifying genetic loci that cause variation
in traits ranging from growth and fitness in simple organisms to disease in humans. However…

Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication

M Carneiro, CJ Rubin, F Di Palma, FW Albert, J Alföldi… - Science, 2014 - science.org
The genetic changes underlying the initial steps of animal domestication are still poorly
understood. We generated a high-quality reference genome for the rabbit and compared it to …

Targeted investigation of the Neandertal genome by array-based sequence capture

…, M Rooks, A Bhattacharjee, L Brizuela, FW Albert… - science, 2010 - science.org
It is now possible to perform whole-genome shotgun sequencing as well as capture of specific
genomic regions for extinct organisms. However, targeted resequencing of large parts of …

Phenotypic differences in behavior, physiology and neurochemistry between rats selected for tameness and for defensive aggression towards humans

FW Albert, O Shchepina, C Winter, H Römpler… - Hormones and …, 2008 - Elsevier
To better understand the biology of tameness, ie tolerance of human presence and handling,
we analyzed two lines of wild-derived rats (Rattus norvegicus) artificially selected for …

[HTML][HTML] Genetic interactions contribute less than additive effects to quantitative trait variation in yeast

…, I Kotenko, MJ Sadhu, S Treusch, FW Albert… - Nature …, 2015 - nature.com
Genetic mapping studies of quantitative traits typically focus on detecting loci that contribute
additively to trait variation. Genetic interactions are often proposed as a contributing factor to …

[HTML][HTML] A comparison of brain gene expression levels in domesticated and wild animals

FW Albert, M Somel, M Carneiro, A Aximu-Petri… - 2012 - journals.plos.org
Domestication has led to similar changes in morphology and behavior in several animal
species, raising the question whether similarities between different domestication events also …

Genetics of single-cell protein abundance variation in large yeast populations

FW Albert, S Treusch, AH Shockley, JS Bloom… - Nature, 2014 - nature.com
Variation among individuals arises in part from differences in DNA sequences, but the
genetic basis for variation in most traits, including common diseases, remains only partly …

Genetic architecture of tameness in a rat model of animal domestication

FW Albert, O Carlborg, I Plyusnina, F Besnier… - Genetics, 2009 - academic.oup.com
Frank W Albert … data from F 0 animals discussed in this article are the same as presented in
Albert … test at 12–14 weeks of age and then followed the testing schedule described in Albert

[HTML][HTML] The genomic architecture of population divergence between subspecies of the European rabbit

M Carneiro, FW Albert, S Afonso, RJ Pereira… - PLoS …, 2014 - journals.plos.org
The analysis of introgression of genomic regions between divergent populations provides
an excellent opportunity to determine the genetic basis of reproductive isolation during the …