[HTML][HTML] Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling

F Wippich, B Bodenmiller, MG Trajkovska, S Wanka… - Cell, 2013 - cell.com
Cytosolic compartmentalization through liquid-liquid unmixing, such as the formation of
RNA granules, is involved in many cellular processes and might be used to regulate signal …

An RNA biosensor for imaging the first round of translation from single cells to living animals

JM Halstead, T Lionnet, JH Wilbertz, F Wippich… - Science, 2015 - science.org
Analysis of single molecules in living cells has provided quantitative insights into the
kinetics of fundamental biological processes; however, the dynamics of messenger RNA (mRNA) …

Enzymatic production of single-molecule FISH and RNA capture probes

I Gaspar, F Wippich, A Ephrussi - Rna, 2017 - rnajournal.cshlp.org
Arrays of singly labeled short oligonucleotides that hybridize to a specific target revolutionized
RNA biology, enabling quantitative, single-molecule microscopy analysis and high-…

Trafficking of the microdomain scaffolding protein reggie-1/flotillin-2

MF Langhorst, A Reuter, FA Jaeger, FM Wippich… - European journal of cell …, 2008 - Elsevier
The reggie/flotillin proteins oligomerize and associate into clusters which form scaffolds for
membrane microdomains. Besides their localization at the plasma membrane, the reggies/…

Terminal deoxynucleotidyl transferase mediated production of labeled probes for single-molecule FISH or RNA capture

I Gaspar, F Wippich, A Ephrussi - Bio-protocol, 2018 - bio-protocol.org
Arrays of short, singly-labeled ssDNA oligonucleotides enable in situ hybridization with
single molecule sensitivity and efficient transcript specific RNA capture. Here, we describe a …

[HTML][HTML] Nutritional stress-induced regulation of microtubule organization and mRNP transport by HDAC1 controlled α-tubulin acetylation

F Wippich, Vaishali, ML Hennrich… - Communications …, 2023 - nature.com
In response to nutritional stress, microtubules in cells of the Drosophila female germline are
depleted from the cytoplasm and accumulate cortically. This triggers aggregation of mRNPs …

[HTML][HTML] Transcript specific mRNP capture from Drosophila egg-chambers for proteomic analysis

F Wippich, A Ephrussi - Methods, 2020 - Elsevier
mRNA binding proteins (RBPs) play a major role in post-transcriptional control of gene
expression. To understand the complex regulatory processes regulating a specific mRNA during …

Leadership in open innovation: examining the influences of open innovation on competencies, control, and behavior in R&D environments

F Wippich - Open Innovation in Firms and Public Administrations …, 2012 - igi-global.com
Frank Wippich … infotainment industry that leads to shorter product life cycles and a
changing competitive landscape (Wippich, 2009). … Wippich, F. (2010). Leadership in …

Dostarlimab shows dose-dependent immune activation of the tumor microenvironment in a patient-derived NSCLC explant model similar to pembrolizumab

J Perrin, F Wippich, V Sherina, D Dvornikov, K Lupar… - Cancer Research, 2023 - AACR
The ability to more faithfully mimic the tumor microenvironment (TME) of cancer patients
offers a wide range of possibilities for non-clinical evaluation of anti-cancer therapeutics, …

Detecting of and Interacting with Text in Free Space.

F Wippich, C Graf, D Drewes - MuC Workshopband, 2013 - degruyter.com
Computer Vision technology has seen a significant push in popularity in consumer applications,
whether for face recognition in today’s smartphone camera apps, or server-based object …