User profiles for Franziska Thomas

Franziska Thomas

Universität Heidelberg
Verified email at chemie.uni-goettingen.de
Cited by 1096

Extensive diversity of Ig-superfamily proteins in the immune system of insects

FL Watson, R Püttmann-Holgado, F Thomas… - Science, 2005 - science.org
The extensive somatic diversification of immune receptors is a hallmark of higher vertebrates.
However, whether molecular diversity contributes to immune protection in invertebrates is …

[HTML][HTML] Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation

J Tcherkezian, PA Brittis, F Thomas, PP Roux… - Cell, 2010 - cell.com
Extracellular signals regulate protein translation in many cell functions. A key advantage of
control at the translational level is the opportunity to regulate protein synthesis within specific …

Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway

F Thomas, U Kutay - Journal of cell science, 2003 - journals.biologists.com
The production of ribosomes constitutes a major biosynthetic task for cells. Eukaryotic small
and large ribosomal subunits are assembled in the nucleolus and independently exported to …

A Set of de Novo Designed Parallel Heterodimeric Coiled Coils with Quantified Dissociation Constants in the Micromolar to Sub-nanomolar Regime

F Thomas, AL Boyle, AJ Burton… - Journal of the American …, 2013 - ACS Publications
The availability of peptide and protein components that fold to defined structures with tailored
stabilities would facilitate rational protein engineering and synthetic biology. We have …

Modular design of self-assembling peptide-based nanotubes

NC Burgess, TH Sharp, F Thomas… - Journal of the …, 2015 - ACS Publications
An ability to design peptide-based nanotubes (PNTs) rationally with defined and mutable
internal channels would advance understanding of peptide self-assembly, and present new …

De Novo-Designed α-Helical Barrels as Receptors for Small Molecules

F Thomas, WM Dawson, EJM Lang… - ACS Synthetic …, 2018 - ACS Publications
We describe de novo-designed α-helical barrels (αHBs) that bind and discriminate between
lipophilic biologically active molecules. αHBs have five or more α-helices arranged around …

Bioconjugation in Materials Science

C Bednarek, U Schepers, F Thomas… - Advanced Functional …, 2023 - Wiley Online Library
With the advent of bioconjugation chemistry in the last two decades, highlighted by the
Nobel Prize 2022, the quest for possible novel applications has been greatly intensified, …

Controlling the assembly of coiled–coil peptide nanotubes

F Thomas, NC Burgess, AR Thomson… - Angewandte Chemie …, 2016 - Wiley Online Library
An ability to control the assembly of peptide nanotubes (PNTs) would provide biomaterials
for applications in nanotechnology and synthetic biology. Recently, we presented a modular …

[PDF][PDF] Autonomous systems in intralogistics–state of the art and future research challenges

…, T Schmidt, K Reith, H Zadek, F Thomas - Journal Logistics …, 2021 - mediatum.ub.tum.de
The paper at hand presents a definition of autonomous intralogistics systems and a
classification of intralogistics systems with regard to their degree of autonomy. Intralogistics− a …

[HTML][HTML] Slit and receptor tyrosine phosphatase 69D confer spatial specificity to axon branching via Dscam1

…, M Petrovic, D Ayaz, H He, Y Kise, F Thomas… - Cell, 2015 - cell.com
Axonal branching contributes substantially to neuronal circuit complexity. Studies in Drosophila
have shown that loss of Dscam1 receptor diversity can fully block axon branching in …