User profiles for Fred B. Berry
Fred BerryUniversity of Alberta Verified email at ualberta.ca Cited by 1616 |
Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld–Rieger syndrome and anterior segment dysgenesis
Axenfeld–Rieger ocular dysgenesis is associated with mutations of the human PITX2 and
FOXC1 genes, which encode transcription factors of the homeodomain and forkhead types, …
FOXC1 genes, which encode transcription factors of the homeodomain and forkhead types, …
FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A
FB Berry, JM Skarie, F Mirzayans… - Human molecular …, 2008 - academic.oup.com
Mutations in the human FOXC1 transcription factor gene underlie Axenfeld–Rieger (AR)
syndrome, a disorder characterized by anterior segment malformations in the eye and glaucoma…
syndrome, a disorder characterized by anterior segment malformations in the eye and glaucoma…
[HTML][HTML] FOXC1 transcriptional regulation is mediated by N-and C-terminal activation domains and contains a phosphorylated transcriptional inhibitory domain
Mutations in the FOXC1 gene result in Axenfeld-Rieger malformations of the anterior segment
of the eye and lead to an increased susceptibility of glaucoma. To understand how the …
of the eye and lead to an increased susceptibility of glaucoma. To understand how the …
[PDF][PDF] Analyses of the effects that disease-causing missense mutations have on the structure and function of the winged-helix protein FOXC1
RA Saleem, S Banerjee-Basu, FB Berry… - The American Journal of …, 2001 - cell.com
Five missense mutations of the winged-helix FOXC1 transcription factor, found in patients
with Axenfeld-Rieger (AR) malformations, were investigated for their effects on FOXC1 …
with Axenfeld-Rieger (AR) malformations, were investigated for their effects on FOXC1 …
[HTML][HTML] Positive and negative regulation of myogenic differentiation of C2C12 cells by isoforms of the multiple homeodomain zinc finger transcription factor ATBF1
FB Berry, Y Miura, K Mihara, P Kaspar, N Sakata… - Journal of Biological …, 2001 - ASBMB
The ATBF1 gene encodes two protein isoforms, the 404-kDa ATBF1-A, possessing four
homeodomains and 23 zinc fingers, and the 306-kDa ATBF1-B, lacking a 920-amino acid N-…
homeodomains and 23 zinc fingers, and the 306-kDa ATBF1-B, lacking a 920-amino acid N-…
Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies
…, Y Sauvé, RK Koenekoop, FB Berry… - Human molecular …, 2013 - academic.oup.com
Retinal dystrophies are predominantly caused by mutations affecting the visual phototransduction
system and cilia, with few genes identified that function to maintain photoreceptor …
system and cilia, with few genes identified that function to maintain photoreceptor …
Structural and functional analyses of disease-causing missense mutations in the forkhead domain of FOXC1
RA Saleem, S Banerjee-Basu, FB Berry… - Human molecular …, 2003 - academic.oup.com
Five missense mutations (P79L, P79T, I91S, I91T and R127H) within the forkhead DNA-binding
domain of the FOXC1 transcription factor, identified in patients with Axenfeld–Rieger (AR…
domain of the FOXC1 transcription factor, identified in patients with Axenfeld–Rieger (AR…
FOXC1 transcriptional regulatory activity is impaired by PBX1 in a filamin A-mediated manner
FB Berry, MA O'Neill, M Coca-Prados… - Molecular and cellular …, 2005 - Taylor & Francis
FOXC1 mutations underlie Axenfeld-Rieger syndrome, an autosomal dominant disorder
that is characterized by a spectrum of ocular and nonocular phenotypes and results in an …
that is characterized by a spectrum of ocular and nonocular phenotypes and results in an …
[HTML][HTML] Severe molecular defects of a novel FOXC1 W152G mutation result in aniridia
YA Ito, TK Footz, FB Berry, F Mirzayans… - … & visual science, 2009 - arvojournals.org
purpose. FOXC1 mutations result in Axenfeld-Rieger syndrome, a disorder characterized by
a broad spectrum of malformations of the anterior segment of the eye and an elevated risk …
a broad spectrum of malformations of the anterior segment of the eye and an elevated risk …
Muscle dysfunction caused by loss of Magel2 in a mouse model of Prader-Willi and Schaaf-Yang syndromes
Prader-Willi syndrome is characterized by severe hypotonia in infancy, with decreased lean
mass and increased fat mass in childhood followed by severe hyperphagia and consequent …
mass and increased fat mass in childhood followed by severe hyperphagia and consequent …