The ability to acquire large-scale recordings of neuronal activity in awake and unrestrained
animals is needed to provide new insights into how populations of neurons generate animal …

The choroid plexus (ChP) in each brain ventricle produces cerebrospinal fluid (CSF) and
forms the blood-CSF barrier. Here, we construct a single-cell and spatial atlas of each ChP in …

Post-hemorrhagic hydrocephalus (PHH) refers to a life-threatening accumulation of
cerebrospinal fluid (CSF) that occurs following intraventricular hemorrhage (IVH). An incomplete …

Cerebrospinal fluid (CSF) provides vital support for the brain. Abnormal CSF accumulation,
such as hydrocephalus, can negatively affect perinatal neurodevelopment. The mechanisms …

Transmission and secretion of signals via the choroid plexus (ChP) brain barrier can modulate
brain states via regulation of cerebrospinal fluid (CSF) composition. Here, we developed …

The choroid plexus (ChP) epithelium is a source of secreted signaling factors in cerebrospinal
fluid (CSF) and a key barrier between blood and brain. Here, we develop imaging tools to …

Understanding how an organism's nervous system transforms sensory input into behavioral
outputs requires recording and manipulating its neural activity during unrestrained behavior. …

For many cancer patients, chemotherapy produces untreatable life-long neurologic effects
termed chemotherapy-related cognitive impairment (CRCI). We discovered that the …

The choroid plexus (ChP) regulates brain development by secreting instructive cues and
providing a protective brain barrier. Here, we show that polyI:C-mediated maternal immune …

The trigeminal sensory innervation of the cranial meninges is thought to serve a nociceptive
function and mediate headache pain. However, the activity of meningeal afferents under …