Aggregation of α‐synuclein (αS) is involved in the pathogenesis of Parkinson's disease (PD)
and a variety of related neurodegenerative disorders. The physiological function of αS is …

Previous studies have identified a crucial role of the gut microbiome in modifying Alzheimer’s
disease (AD) progression. However, the mechanisms of microbiome–brain interaction in …

Revised Manuscript Received July 8, 1993* abstract: How lipophilic acids move across
membranes, either model or biological, is the subject of controversy. We describe experiments …

Revised Manuscript Received June 26, 1995® abstract: The rate of movement of fatty acids (FA)
across phospholipid bilayers is an important consideration for their mechanism of …

Although transport of long-chain free fatty acids (FFAs) into cells is often analyzed in the same
way as glucose transport, we argue that the transport of the lipid-soluble amphipathic FFA …

A central, unresolved question in cell physiology is how fatty acids move across cell
membranes and whether protein(s) are required to facilitate transbilayer movement. We have …

The perpetuation of inflammation is an important pathophysiological contributor to the global
medical burden. Chronic inflammation is promoted by non-programmed cell death 1 , 2 ; …

Alpha-synuclein (αS) is a 140-amino-acid protein that is involved in a number of neurodegenerative
diseases. In Parkinson's disease, the protein is typically encountered in intracellular, …

A number of neurodegenerative disorders, including Parkinson's disease, dementia with
Lewy bodies, and multiple system atrophy, are characterized by the intracellular deposition of …

Opposing views exist as to how unesterified fatty acids (FA) enter and leave cells. It is
commonly believed that for short- and medium-chain FA free diffusion suffices whereas it is …