[HTML][HTML] Brainstem organoids from human pluripotent stem cells

…, T Komeda, N Morikawa, F Kitayoshi… - Frontiers in …, 2020 - frontiersin.org
The brainstem is a posterior region of the brain, composed of three parts, midbrain, pons, and
medulla oblongata. It is critical in controlling heartbeat, blood pressure, and respiration, all …

[HTML][HTML] Inhibition of the ATR kinase enhances 5-FU sensitivity independently of nonhomologous end-joining and homologous recombination repair pathways

…, H Nanaura, M Nakanishi, F Kitayoshi… - Journal of Biological …, 2020 - ASBMB
The anticancer agent 5-fluorouracil (5-FU) is cytotoxic and often used to treat various
cancers. 5-FU is thought to inhibit the enzyme thymidylate synthase, which plays a role in …

Brainstem organoids from human pluripotent stem cells contain neural crest population

…, R Nagata, T Komeda, N Morikawa, F Kitayoshi… - bioRxiv, 2019 - biorxiv.org
The brainstem controls heartbeat, blood pressure and respiration, which are life-sustaining
functions, therefore, disorders of the brainstem can be lethal. Brain organoids derived from …

ATR inhibition enhances 5-fluorouracil sensitivity independent of non-homologous end-joining and homologous recombination repair pathway

…, TK Matsui, H Nanaura, M Nakanishi, F Kitayoshi… - bioRxiv, 2020 - biorxiv.org
The anticancer agent, 5-fluorouracil (5-FU), is typically applied in the treatment of various types
of cancers because of its properties. Thought to be an inhibitor of the enzyme thymidylate …

[PDF][PDF] https://www. jbc. org/cgi/doi/10.1074/jbc. RA120. 013726 The latest version is at

…, TK Matsui, H Nanaura, M Nakanishi, F Kitayoshi… - academia.edu
The anticancer agent 5-fluorouracil (5-FU) is cytotoxic and often used to treat various
cancers. 5-FU is thought to inhibit the enzyme thymidylate synthase, which plays a role in …

MIF Inhibition Suppresses Cell Viability and Induces Apoptosis via the ATF4-CHOP Pathway in Mouse Pituitary AtT-20 Cells

…, T Tateno, S Willette, RZ Yang, F Kitayoshi… - Journal of the …, 2021 - ncbi.nlm.nih.gov
Cushing’s disease (CD) is characterized by cortisol overproduction due to ACTH hypersecretion
from a pituitary tumour (PT). With an incidence of approximately 1.2 to 2.4 cases per …

[PDF][PDF] Brainstem Organoids From Human Pluripotent Stem Cells

…, R Nagata, T Komeda, N Morikawa, F Kitayoshi… - scienceopen.com
The brainstem is a posterior region of the brain, composed of three parts, midbrain, pons, and
medulla oblongata. It is critical in controlling heartbeat, blood pressure, and respiration, all …

[PDF][PDF] Brainstem organoids from human pluripotent stem cells contain neural crest population

N Eura, TK Matsui, J Luginbühl, M Matsubayashi… - academia.edu
The brainstem controls heartbeat, blood pressure and respiration, which are life-sustaining
functions, therefore, disorders of the brainstem can be lethal. Brain organoids derived from …

Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge that Promotes Resistance in Male Offspring to a High Fat Diet

TK Miles, ML Allensworth, ARS Moreira… - Journal of the …, 2021 - academic.oup.com
Malnutrition alters leptin signaling, resulting in dysregulation of pituitary somatotropes that
may be sex-specific. We reported sex differences in acute fasting responses with reductions in …

[PDF][PDF] Neuroendocrinology and Pituitary

S Willette - academia.edu
Cushing’s disease (CD) is characterized by cortisol overproduction due to ACTH hypersecretion
from a pituitary tumour (PT). With an incidence of approximately 1.2 to 2.4 cases per …