Directed evolution of an α1, 3-fucosyltransferase using a single-cell ultrahigh-throughput screening method

Y Tan, Y Zhang, Y Han, H Liu, H Chen, F Ma… - Science …, 2019 - science.org
Fucosylated glycoconjugates are involved in a variety of physiological and pathological
processes. However, economical production of fucosylated drugs and prebiotic supplements …

Genome-wide screen identifies curli amyloid fibril as a bacterial component promoting host neurodegeneration

C Wang, CY Lau, F Ma… - Proceedings of the …, 2021 - National Acad Sciences
Growing evidence indicates that gut microbiota play a critical role in regulating the progression
of neurodegenerative diseases such as Parkinson’s disease. The molecular mechanism …

Transcriptome age of individual cell types in Caenorhabditis elegans

F Ma, C Zheng - Proceedings of the National Academy of …, 2023 - National Acad Sciences
The phylotranscriptomic analysis of development in several species revealed the expression
of older and more conserved genes in midembryonic stages and younger and more …

Fluorescence coupling strategies in fluorescence-activated droplet sorting (FADS) for ultrahigh-throughput screening of enzymes, metabolites, and antibodies

J Jiang, G Yang, F Ma - Biotechnology advances, 2023 - Elsevier
Fluorescence-activated droplet sorting (FADS) has emerged as a powerful tool for ultrahigh-throughput
screening of enzymes, metabolites, and antibodies. Fluorescence coupling …

Large Genetic Diversity and Strong Positive Selection in F-Box and GPCR Genes among the Wild Isolates of Caenorhabditis elegans

F Ma, CY Lau, C Zheng - Genome Biology and Evolution, 2021 - academic.oup.com
The F-box and chemosensory GPCR (csGPCR) gene families are greatly expanded in
nematodes, including the model organism Caenorhabditis elegans, compared with insects and …

[HTML][HTML] Efficient molecular evolution to generate enantioselective enzymes using a dual-channel microfluidic droplet screening platform

F Ma, MT Chung, Y Yao, R Nidetz, LM Lee… - Nature …, 2018 - nature.com
Directed evolution has long been a key strategy to generate enzymes with desired properties
like high selectivity, but experimental barriers and analytical costs of screening enormous …

Wideband DOA estimation based on focusing signal subspace

F Ma, X Zhang - Signal, Image and Video Processing, 2019 - Springer
The traditional wideband direction-of-arrival (DOA) estimation algorithms usually require the
preliminary DOA estimations, which determine the accuracy of the final DOA estimations. To …

[HTML][HTML] All-in-one digital microfluidics system for molecular diagnosis with loop-mediated isothermal amplification

…, K Jin, Y Zhang, T Guo, Q Huang, Q Mei, F Ma, H Ma - Biosensors, 2022 - mdpi.com
In this study, an “all-in-one” digital microfluidics (DMF) system was developed for automatic
and rapid molecular diagnosis and integrated with magnetic bead-based nucleic acid …

Ring-opening polymerization of ɛ-caprolactone catalyzed by a novel thermophilic lipase from Fervidobacterium nodosum

Q Li, G Li, S Yu, Z Zhang, F Ma, Y Feng - Process Biochemistry, 2011 - Elsevier
The paper explored the catalytic activity of a novel thermophilic lipase from Fervidobacterium
nodosum for polyester synthesis, using the ring-opening polymerization of ɛ-caprolactone …

A distributed TDMA scheduling algorithm based on energy-topology factor in Internet of Things

Y Li, X Zhang, J Zeng, Y Wan, F Ma - IEEE Access, 2017 - ieeexplore.ieee.org
In Internet of Things, various things realize interconnection and intercommunication by the
wireless sensor network (WSN). The time-division multiple-access (TDMA) slot scheduling …