User profiles for Fuzhong Zhang
Fuzhong ZhangProfessor, Washington University in St. Louis Verified email at seas.wustl.edu Cited by 7983 |
Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids
Microbial production of chemicals is now an attractive alternative to chemical synthesis. Current
efforts focus mainly on constructing pathways to produce different types of molecules 1 , …
efforts focus mainly on constructing pathways to produce different types of molecules 1 , …
Recombinant spidroins fully replicate primary mechanical properties of natural spider silk
Despite significant efforts to engineer their heterologous production, recombinant spider silk
proteins (spidroins) have yet to replicate the unparalleled combination of high strength and …
proteins (spidroins) have yet to replicate the unparalleled combination of high strength and …
A biosynthetic hybrid spidroin-amyloid-mussel foot protein for underwater adhesion on diverse surfaces
Strong underwater adhesives are attractive materials for biomedical healing and underwater
repair, but their success in applications has been limited, owing to challenges with …
repair, but their success in applications has been limited, owing to challenges with …
Negative feedback regulation of fatty acid production based on a malonyl-CoA sensor–actuator
Engineering metabolic biosynthetic pathways has enabled the microbial production of many
useful chemicals. However, pathway productivities and yields are often limited by metabolic …
useful chemicals. However, pathway productivities and yields are often limited by metabolic …
Microbial engineering for the production of advanced biofuels
PP Peralta-Yahya, F Zhang, SB Del Cardayre… - Nature, 2012 - nature.com
Advanced biofuels produced by microorganisms have similar properties to petroleum-based
fuels, and can 'drop in' to the existing transportation infrastructure. However, producing …
fuels, and can 'drop in' to the existing transportation infrastructure. However, producing …
Engineering dynamic pathway regulation using stress-response promoters
Heterologous pathways used in metabolic engineering may produce intermediates toxic to
the cell. Dynamic control of pathway enzymes could prevent the accumulation of these …
the cell. Dynamic control of pathway enzymes could prevent the accumulation of these …
[HTML][HTML] BglBrick vectors and datasheets: a synthetic biology platform for gene expression
Background As engineered biological systems become more complex, it is increasingly
common to express multiple operons from different plasmids and inducible expression systems …
common to express multiple operons from different plasmids and inducible expression systems …
Metabolic engineering of microbial pathways for advanced biofuels production
F Zhang, S Rodriguez, JD Keasling - Current opinion in biotechnology, 2011 - Elsevier
Production of biofuels from renewable resources such as cellulosic biomass provides a source
of liquid transportation fuel to replace petroleum-based fuels. This endeavor requires the …
of liquid transportation fuel to replace petroleum-based fuels. This endeavor requires the …
Microbially synthesized polymeric amyloid fiber promotes β-nanocrystal formation and displays gigapascal tensile strength
The ability of amyloid proteins to form stable β-sheet nanofibrils has made them potential
candidates for material innovation in nanotechnology. However, such a nanoscale feature has …
candidates for material innovation in nanotechnology. However, such a nanoscale feature has …
Spectral tuning of azobenzene photoswitches for biological applications
O Sadovski, AA Beharry, F Zhang… - Angewandte Chemie …, 2009 - Wiley Online Library
Longer switching wavelengths and good photochemical yields and stabilities of the cis
isomers in reducing aqueous environments are achieved by introducing 2,2′‐aminoalkyl …
isomers in reducing aqueous environments are achieved by introducing 2,2′‐aminoalkyl …