The cortex is a thin, crosslinked actin network lying immediately beneath the plasma membrane
of animal cells. Myosin motors exert contractile forces in the meshwork. Because the …

Blebs are spherical membrane protrusions that are produced by contractions of the actomyosin
cortex. Blebs are often considered to be a hallmark of apoptosis; however, blebs are also …

Blebs are protrusions of the cell membrane. They are the result of actomyosin contractions
of the cortex, which cause either transient detachment of the cell membrane from the actin …

Animal cell shape is largely determined by the cortex, a thin actin network underlying the
plasma membrane in which myosin-driven stresses generate contractile tension. Tension …

Contractile actin cortex is involved in cell morphogenesis, movement, and cytokinesis, but
its organization and assembly are poorly understood. During blebbing, the membrane …

Current models for protrusive motility in animal cells focus on cytoskeleton-based mechanisms,
where localized protrusion is driven by local regulation of actin biochemistry 1 , 2 , 3 . In …

To learn more about cancer-associated fibroblasts (CAFs), we have isolated fibroblasts from
different stages of breast cancer progression and analysed their function and gene …

The cytoplasm is the largest part of the cell by volume and hence its rheology sets the rate
at which cellular shape changes can occur. Recent experimental evidence suggests that …

The way in which a cell migrates is influenced by the physical properties of its surroundings,
in particular the properties of the extracellular matrix. How the physical aspects of the cell's …

Blebs are spherical cellular protrusions that occur in many physiological situations. Two
distinct phases make up the life of a bleb, each of which have their own biology and physics: …