User profiles for G. D. Horwitz

Greg Horwitz

University of Washington
Verified email at u.washington.edu
Cited by 3944

[HTML][HTML] Comparative cellular analysis of motor cortex in human, marmoset and mouse

…, J Gillis, R Hertzano, PR Hof, T Höllt, GD Horwitz… - Nature, 2021 - nature.com
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally
conserved across mammals 1 . Here, using high-throughput transcriptomic and epigenomic …

Separate signals for target selection and movement specification in the superior colliculus

GD Horwitz, WT Newsome - Science, 1999 - science.org
At any given instant, multiple potential targets for saccades are present in the visual world,
implying that a “selection process” within the brain determines the target of the next eye …

Advances in color science: from retina to behavior

…, S Chatterjee, GD Field, GD Horwitz… - Journal of …, 2010 - Soc Neuroscience
Color has become a premier model system for understanding how information is processed
by neural circuits, and for investigating the relationships among genes, neural circuits, and …

Target selection for saccadic eye movements: prelude activity in the superior colliculus during a direction-discrimination task

GD Horwitz, WT Newsome - Journal of neurophysiology, 2001 - journals.physiology.org
GD Horwitz was supported by a graduate research fellowship from the Office of Naval
Research and by a training grant from the National Institute of Mental Health (MH-17047). …

Saccadic eye movements evoked by optogenetic activation of primate V1

M Jazayeri, Z Lindbloom-Brown, GD Horwitz - Nature neuroscience, 2012 - nature.com
Optogenetics has advanced our understanding of the neural basis of simple behaviors in
rodents and small animals. In primates, however, for which more sophisticated behavioral …

Representation of an abstract perceptual decision in macaque superior colliculus

GD Horwitz, AP Batista… - Journal of …, 2004 - journals.physiology.org
GD Horwitz was supported by a training grant from the National Institute of Mental Health
(MH-17047). AP Batista was supported by the Howard Hughes Medical Institute. WT Newsome …

Single-cell and single-nucleus RNA-seq uncovers shared and distinct axes of variation in dorsal LGN neurons in mice, non-human primates, and humans

…, Z Yao, TN Nguyen, LT Graybuck, GD Horwitz… - Elife, 2021 - elifesciences.org
Abundant evidence supports the presence of at least three distinct types of thalamocortical (TC)
neurons in the primate dorsal lateral geniculate nucleus (dLGN) of the thalamus, the …

[PDF][PDF] Viral vectors for neural circuit mapping and recent advances in trans-synaptic anterograde tracers

X Xu, TC Holmes, MH Luo, KT Beier, GD Horwitz… - Neuron, 2020 - cell.com
Viral tracers are important tools for neuroanatomical mapping and genetic payload delivery.
Genetically modified viruses allow for cell-type-specific targeting and overcome many …

[PDF][PDF] Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex

…, DL Silbergeld, SM Sunkin, V Gradinaru, GD Horwitz… - Cell reports, 2021 - cell.com
Viral genetic tools that target specific brain cell types could transform basic neuroscience
and targeted gene therapy. Here, we use comparative open chromatin analysis to identify …

Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse

…, J Gillis, R Hertzano, PR Hof, T Höllt, GD Horwitz… - BioRxiv, 2020 - biorxiv.org
The primary motor cortex (M1) is essential for voluntary fine motor control and is functionally
conserved across mammals. Using high-throughput transcriptomic and epigenomic profiling …