Repair of UV damage in bacteria
N Goosen, GF Moolenaar - DNA repair, 2008 - Elsevier
From the start of the first primitive life forms on earth ultraviolet (UV) light has been a seriously
threatening factor. UV light is absorbed by the DNA causing several types of damage that …
threatening factor. UV light is absorbed by the DNA causing several types of damage that …
Role of ATP hydrolysis by UvrA and UvrB during nucleotide excision repair
N Goosen, GF Moolenaar - Research in microbiology, 2001 - Elsevier
Nucleotide excision repair in eubacteria is a process that repairs DNA damages by the removal
of a 12–13-mer oligonucleotide containing the lesion. Recognition and cleavage of the …
of a 12–13-mer oligonucleotide containing the lesion. Recognition and cleavage of the …
[HTML][HTML] Catalytic sites for 3′ and 5′ incision of Escherichia coli nucleotide excision repair are both located in UvrC
EEA Verhoeven, M van Kesteren, GF Moolenaar… - Journal of Biological …, 2000 - ASBMB
Nucleotide excision repair in Escherichia coli is a multistep process in which DNA damage
is removed by incision of the DNA on both sides of the damage, followed by removal of the …
is removed by incision of the DNA on both sides of the damage, followed by removal of the …
[HTML][HTML] The presence of two UvrB subunits in the UvrAB complex ensures damage detection in both DNA strands
EEA Verhoeven, C Wyman, GF Moolenaar… - The EMBO …, 2002 - embopress.org
It is generally accepted that the damage recognition complex of nucleotide excision repair
in Escherichia coli consists of two UvrA and one UvrB molecule, and that in the preincision …
in Escherichia coli consists of two UvrA and one UvrB molecule, and that in the preincision …
Effect of temperature on the intrinsic flexibility of DNA and its interaction with architectural proteins
The helical structure of double-stranded DNA is destabilized by increasing temperature.
Above a critical temperature (the melting temperature), the two strands in duplex DNA become …
Above a critical temperature (the melting temperature), the two strands in duplex DNA become …
Mechanism of environmentally driven conformational changes that modulate H-NS DNA-bridging activity
RA van der Valk, J Vreede, L Qin, GF Moolenaar… - Elife, 2017 - elifesciences.org
10.7554/eLife.27369.001 Bacteria frequently need to adapt to altered environmental conditions.
Adaptation requires changes in gene expression, often mediated by global regulators of …
Adaptation requires changes in gene expression, often mediated by global regulators of …
[PDF][PDF] Crystal structure of Bacillus stearothermophilus UvrA provides insight into ATP-modulated dimerization, UvrB interaction, and DNA binding
…, Y Inuzuka, BR Bowman, GF Moolenaar… - Molecular cell, 2008 - cell.com
The nucleotide excision repair pathway corrects many structurally unrelated DNA lesions.
Damage recognition in bacteria is performed by UvrA, a member of the ABC ATPase …
Damage recognition in bacteria is performed by UvrA, a member of the ABC ATPase …
Role of the Escherichia coli Nucleotide Excision Repair Proteins in DNA Replication
GF Moolenaar, C Moorman, N Goosen - Journal of bacteriology, 2000 - Am Soc Microbiol
DNA polymerase I (PolI) functions both in nucleotide excision repair (NER) and in the processing
of Okazaki fragments that are generated on the lagging strand during DNA replication.…
of Okazaki fragments that are generated on the lagging strand during DNA replication.…
[HTML][HTML] The C-terminal Region of the UvrB Protein of Escherichia coli Contains an Important Determinant for UvrC Binding to the Preincision Complex but Not the …
GF Moolenaar, KLMC Franken, DM Dijkstra… - Journal of Biological …, 1995 - ASBMB
The UvrABC endonuclease from Escherichia coli repairs damage in the DNA by dual incision
of the damaged strand on both sides of the lesion. The incisions are in an ordered fashion, …
of the damaged strand on both sides of the lesion. The incisions are in an ordered fashion, …
Cho, a second endonuclease involved in Escherichia coli nucleotide excision repair
GF Moolenaar, S van Rossum-Fikkert… - Proceedings of the …, 2002 - National Acad Sciences
Nucleotide excision repair removes damages from the DNA by incising the damaged strand
on the 3′ and 5′ sides of the lesion. In Escherichia coli, the two incisions are made by the …
on the 3′ and 5′ sides of the lesion. In Escherichia coli, the two incisions are made by the …