PPAR-γ agonists: therapeutic role in diabetes, inflammation and cancer
GJ Murphy, JC Holder - Trends in pharmacological sciences, 2000 - cell.com
The recent development of a novel class of insulin-sensitizing drugs, the thiazolidinediones (TZDs),
represents a significant advance in antidiabetic therapy. One key mechanism by …
represents a significant advance in antidiabetic therapy. One key mechanism by …
[HTML][HTML] Universal definition of perioperative bleeding in adult cardiac surgery
Objectives Perioperative bleeding is common among patients undergoing cardiac surgery;
however, the definition of perioperative bleeding is variable and lacks standardization. We …
however, the definition of perioperative bleeding is variable and lacks standardization. We …
Side effects of cardiopulmonary bypass: what is the reality?
GJ Murphy, GD Angelini - Journal of cardiac surgery, 2004 - Wiley Online Library
Despite many years of clinical and experimental research, the contribution of cardiopulmonary
bypass (CPB) and cardioplegic arrest to morbidity and mortality following cardiac surgery …
bypass (CPB) and cardioplegic arrest to morbidity and mortality following cardiac surgery …
[BOOK][B] C*-algebras and operator theory
GJ Murphy - 2014 - books.google.com
This book constitutes a first-or second-year graduate course in operator theory. It is a field
that has great importance for other areas of mathematics and physics, such as algebraic …
that has great importance for other areas of mathematics and physics, such as algebraic …
Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery
Background— Red blood cell transfusion can both benefit and harm. To inform decisions
about transfusion, we aimed to quantify associations of transfusion with clinical outcomes and …
about transfusion, we aimed to quantify associations of transfusion with clinical outcomes and …
[PDF][PDF] Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
…, JW Yates, NJ Pearce, OL Rausch, GJ Murphy… - Chemistry & biology, 2000 - cell.com
Background: Glycogen synthase kinase-3 (GSK-3) is a serine/threonine protein kinase, the
activity of which is inhibited by a variety of extracellular stimuli including insulin, growth factors…
activity of which is inhibited by a variety of extracellular stimuli including insulin, growth factors…
Induced pluripotent stem cell generation using a single lentiviral stem cell cassette
Induced pluripotent stem (iPS) cells can be generated using retroviral vectors expressing
Oct4, Klf4, Sox2, and cMyc. Most prior studies have required multiple retroviral vectors for …
Oct4, Klf4, Sox2, and cMyc. Most prior studies have required multiple retroviral vectors for …
[HTML][HTML] Liberal or restrictive transfusion after cardiac surgery
Background Whether a restrictive threshold for hemoglobin level in red-cell transfusions, as
compared with a liberal threshold, reduces postoperative morbidity and health care costs …
compared with a liberal threshold, reduces postoperative morbidity and health care costs …
[PDF][PDF] A suite of transgenic driver and reporter mouse lines with enhanced brain-cell-type targeting and functionality
Modern genetic approaches are powerful in providing access to diverse cell types in the brain
and facilitating the study of their function. Here, we report a large set of driver and reporter …
and facilitating the study of their function. Here, we report a large set of driver and reporter …
[PDF][PDF] Integrated morphoelectric and transcriptomic classification of cortical GABAergic cells
Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …
or genetic attributes. To better constrain the definition of neuronal cell types, we …