The widespread use of high-resolution computed tomography in clinical and research settings
has increased the detection of interstitial lung abnormalities (ILA) in asymptomatic and …

Hispanic individuals trace their ancestry to countries that were previously under Spanish rule,
including Mexico, large parts of Central and South America, and some Caribbean islands. …

Rationale: Maternal vitamin D intake during pregnancy has been inversely associated with
asthma symptoms in early childhood. However, no study has examined the relationship …

Genetic studies hold promise in helping to identify patients with early idiopathic pulmonary
fibrosis (IPF). Recent studies using chest computed tomograms (CTs) in smokers and in the …

… Using genetically modified mice, we demonstrate that caspase-1–dependent inflammasome
cytokine responses are critical to the propagation of ALI in a rodent model of VILI. This …

The term interstitial lung abnormalities refers to specific CT findings that are potentially
compatible with interstitial lung disease in patients without clinical suspicion of the disease. …

Background Cigarette smoking is associated with emphysema and radiographic interstitial
lung abnormalities. The degree to which interstitial lung abnormalities are associated with …

EC activation and dysfunction have been linked to a variety of vascular inflammatory disease
states. The function of microRNAs (miRNAs) in vascular EC activation and inflammation …

Background Genetic variants influencing lung function in children and adults may ultimately
lead to the development of chronic obstructive pulmonary disease (COPD), particularly in …

We performed a genome-wide association study for chronic obstructive pulmonary disease (COPD)
in three population cohorts, including 2,940 cases and 1,380 controls who were …