User profiles for G. S. Barsh
 | Gregory BarshProfessor of Genetics, Stanford University Verified email at stanford.edu Cited by 47904 |
Central nervous system control of food intake and body weight
The capacity to adjust food intake in response to changing energy requirements is essential
for survival. Recent progress has provided an insight into the molecular, cellular and …
for survival. Recent progress has provided an insight into the molecular, cellular and …
Genetics of body-weight regulation
The role of genetics in obesity is twofold. Studying rare mutations in humans and model
organisms provides fundamental insight into a complex physiological process, and …
organisms provides fundamental insight into a complex physiological process, and …
Weight loss regulates inflammation‐related genes in white adipose tissue of obese subjects
… For microarray experiments, 1 g of total RNA from each total RNA sample preparation was
amplified by MessageAmp RNA Kit (Ambion, Austin, TX, USA) and 3 g of amplified RNA was …
amplified by MessageAmp RNA Kit (Ambion, Austin, TX, USA) and 3 g of amplified RNA was …
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
… At 11 weeks of age, female F 0 animals weighed 30.5, 35.5, and 41.9 g, and male F 0
animals weighed 32.4, 34.8, and 43 g—significantly more than nontransgenic littermates (females: …
animals weighed 32.4, 34.8, and 43 g—significantly more than nontransgenic littermates (females: …
Worldwide human relationships inferred from genome-wide patterns of variation
Human genetic diversity is shaped by both demographic and biological factors and has
fundamental implications for understanding the genetic basis of diseases. We studied 938 …
fundamental implications for understanding the genetic basis of diseases. We studied 938 …
Mitochondrial transcription factor A is necessary for mtDNA maintance and embryogenesis in mice
The regulation of mitochondrial DNA (mtDNA) expression is crucial for mitochondrial
biogenesis during development and differentiation. We have disrupted the mouse gene for …
biogenesis during development and differentiation. We have disrupted the mouse gene for …
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
… Here we report frequent somatic mutations in the heterotrimeric G protein α-subunit,
GNAQ, in blue naevi (83%) and ocular melanoma of the uvea (46%). The mutations occur …
GNAQ, in blue naevi (83%) and ocular melanoma of the uvea (46%). The mutations occur …
Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight …
In human obesity, the stroma vascular fraction (SVF) of white adipose tissue (WAT) is
enriched in macrophages. These cells may contribute to low-grade inflammation and to its …
enriched in macrophages. These cells may contribute to low-grade inflammation and to its …
Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area
…, GE Hoffman, MM Ollmann, GS Barsh… - Journal of …, 1998 - Wiley Online Library
… F,G: MCH-IR terminals are present in the mammillary body and in the insular cortex. For
abbreviations, see list. A–C are at same the magnification, and F and G … E–G: ORX-IR terminals …
abbreviations, see list. A–C are at same the magnification, and F and G … E–G: ORX-IR terminals …
Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in mice
L Hein, GS Barsh, RE Pratt, VJ Dzau, BK Kobilka - Nature, 1995 - nature.com
ANGIOTENSIN II, a potent regulator of blood pressure and of water and electrolyte balance,
binds to two different G-protein-coupled receptors. The type-1 receptor (AT 1 ,) mediates the …
binds to two different G-protein-coupled receptors. The type-1 receptor (AT 1 ,) mediates the …