Complex I is the first and largest enzyme of the respiratory chain and has a central role in
cellular energy production through the coupling of NADH:ubiquinone electron transfer to …

… Minhas, Simon Newstead; Recent advances in understanding prodrug transport through
the SLC15 family of proton-coupled transporters. Biochem Soc Trans 29 April 2020; 48 (2): 337…

… by centrifugation (6800×g for 30 min, at 4 C) and resuspended in 5 mL/g of cells of binding …
C for 10 min, then clarified by ultracentrifugation (215,000×g for 1 h at 23 C). The supernatant …

… bind G-quadruplex DNA with a high degree of specificity, with the G-quadruplex binding
behavior being lost upon reduction of the oxazole number from six to four. Results from G-…

A major challenge in drug development is the optimization of intestinal absorption and cellular
uptake. A successful strategy has been to develop prodrug molecules, which hijack solute …

… 30,000 x g for 30 min, and membranes were isolated by ultracentrifugation at 230,000 x g for
… Non-solubilised membranes were removed by ultracentrifugation at 230,000 g for 60 min. …

Background Experience with public engagement activities regarding the risks and benefits
of science and technology (S&T) is growing, especially in the industrialized world. However, …

… To a mixture of 4.33 g (27 mmol) of diethyl malonate in 25 mL of THF was sequentially
added 1.14 g (28.5 mmol) of 60% NaH/mineral oil and 5.37 g (27 mmol) of (3-bromopropyl)…

Chemical, physical and inversion characteristics of quartzites from different sources have
been studied to evaluate their suitability for the conventional as well as superduty type of silica …

Background Autoimmune Enteropathy is a rare condition characterized by clinical symptoms
of intractable diarrhea, vomiting, and weight loss that often results in malnutrition. It is …