… The deaminase catalyzes a C to T (G to A) and A to G (T to C) conversion in the target
window. Deamination of cytidine results in uridine, which is converted to thymine after DNA …

Oxidative stress and inflammation cannot be considered as diseases themselves; however,
they are major risk factors for the development and progression of the pathogenesis …

We describe an MHC class II (IA b)–restricted TCR transgenic mouse line that produces CD4+
T cells specific for Plasmodium species. This line, termed PbT-II, was derived from a CD4…

Rett syndrome (RTT) is a severe X-linked dominant neurodevelopmental disorder caused
by mutations in the methyl-CpG-binding protein 2 (MECP2) gene; MeCP2 regulates the …

Upon activation, specific CD4 + T cells up-regulate the expression of CD11a and CD49d,
surrogate markers of pathogen-specific CD4 + T cells. However, using T-cell receptor …

… Cytosine base editors are able to convert C to T, as well as corresponding G to A in the
opposite strand of DNA, while producing intermediate U conversion by deaminases, which can …

Malaria infection elicits both protective and pathogenic immune responses, and IL‐27 is a
critical cytokine that regulate effector responses during infection. Here, we identified a critical …

… To prepare BSA solution at 10 mg mL −1 concentration, 0.10 g of BSA was directly dissolved
in … For preparing egg white protein solution, 37.5 g of egg white was separated from the yolk …

Adaptive immune responses are critical for protection against infection with Plasmodium
parasites. The metabolic state dramatically changes in T cells during activation and the memory …

Thorough understanding of the role of CD4 T cells in immunity can be greatly assisted by
the study of responses to defined specificities. This requires knowledge of Plasmodium-derived …